Predicted to enable dynein light chain binding activity. Predicted to be involved in cilium assembly; embryonic skeletal system morphogenesis; and intraciliary retrograde transport. Predicted to be located in ciliary base and microtubule cytoskeleton. Predicted to be part of cytoplasmic dynein complex. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1).
RGD Description
Predicted to enable dynein light chain binding activity. Predicted to be involved in cilium assembly; embryonic skeletal system morphogenesis; and intraciliary retrograde transport. Predicted to be located in ciliary base and microtubule cytoskeleton. Predicted to be part of cytoplasmic dynein complex. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.