Gene

Tmem63c

Species
Rattus norvegicus
Symbol
Tmem63c
Name
transmembrane protein 63c
Synonyms
  • calcium permeable stress-gated cation channel 1
  • LOC314332
Biotype
protein coding gene
Automated Description
Predicted to enable calcium-activated cation channel activity and osmolarity-sensing monoatomic cation channel activity. Involved in glomerular filtration. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 87. Orthologous to human TMEM63C (transmembrane protein 63C).
RGD Description
Predicted to enable calcium-activated cation channel activity and osmolarity-sensing monoatomic cation channel activity. Involved in glomerular filtration. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 87. Orthologous to human TMEM63C (transmembrane protein 63C); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13018
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
106.67M106.68M106.69M106.70M106.71M106.72M106.73M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions