Gene

Pgam5

Species
Rattus norvegicus
Symbol
Pgam5
Name
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Synonyms
  • LOC288731
  • phosphoglycerate mutase family member 5
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase activator activity and protein serine/threonine phosphatase activity. Predicted to be involved in several processes, including necroptotic process; negative regulation of cold-induced thermogenesis; and positive regulation of mitochondrial fission. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human PGAM5 (PGAM family member 5, mitochondrial serine/threonine protein phosphatase).
RGD Description
Predicted to enable GTPase activator activity and protein serine/threonine phosphatase activity. Predicted to be involved in several processes, including necroptotic process; negative regulation of cold-induced thermogenesis; and positive regulation of mitochondrial fission. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human PGAM5 (PGAM family member 5, mitochondrial serine/threonine protein phosphatase); PARTICIPATES IN mitochondrial autophagy pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20935
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
46.410M46.411M46.412M46.413M46.414M46.415M46.416M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions