Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; positive regulation of calcineurin-NFAT signaling cascade; and proteolysis. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane; plasma membrane; and rough endoplasmic reticulum. Predicted to be active in Golgi-associated vesicle membrane; cytoplasmic side of endoplasmic reticulum membrane; and lumenal side of endoplasmic reticulum membrane. Orthologous to human SPPL3 (signal peptide peptidase like 3).
RGD Description
Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; positive regulation of calcineurin-NFAT signaling cascade; and signal peptide processing. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane; plasma membrane; and rough endoplasmic reticulum. Predicted to be active in Golgi-associated vesicle membrane; cytoplasmic side of endoplasmic reticulum membrane; and lumenal side of endoplasmic reticulum membrane. Orthologous to human SPPL3 (signal peptide peptidase like 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; bisphenol A.