Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and modification-dependent protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein folding; and regulation of protein metabolic process. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2).
RGD Description
Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and modification-dependent protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein folding; and regulation of protein metabolic process. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.