Gene

Dnajb2

Species
Rattus norvegicus
Symbol
Dnajb2
Name
DnaJ heat shock protein family (Hsp40) member B2
Synonyms
  • DnaJ (Hsp40) homolog, subfamily B, member 2
  • dnaJ homolog subfamily B member 2
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and modification-dependent protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein folding; and regulation of protein metabolic process. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2).
RGD Description
Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and modification-dependent protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein folding; and regulation of protein metabolic process. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45168
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
76.732M76.733M76.734M76.735M76.736M76.737M76.738M76.739M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions