Gene

Ascl2

Species
Rattus norvegicus
Symbol
Ascl2
Name
achaete-scute family bHLH transcription factor 2
Synonyms
  • achaete-scute complex homolog 2
  • achaete-scute complex homolog 2 (Drosophila)
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription factor activity. Involved in negative regulation of Schwann cell proliferation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human ASCL2 (achaete-scute family bHLH transcription factor 2).
RGD Description
Enables DNA-binding transcription factor activity. Involved in negative regulation of Schwann cell proliferation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human ASCL2 (achaete-scute family bHLH transcription factor 2); INTERACTS WITH (S)-nicotine; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19290
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
198.1490M198.1492M198.1494M198.1496M198.1498M198.1500M198.1502M198.1504M198.1506M198.1508M198.1510M198.1512M198.1514M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions