Gene

Mecr

Species
Rattus norvegicus
Symbol
Mecr
Name
mitochondrial trans-2-enoyl-CoA reductase
Synonyms
  • 2-enoyl thioester reductase
  • enoyl-[acyl-carrier-protein] reductase, mitochondrial
Biotype
protein coding gene
Automated Description
Enables signaling receptor binding activity. Predicted to be involved in fatty acid metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in childhood-onset dystonia with optic atrophy and basal ganglia abnormalities and optic atrophy. Orthologous to human MECR (mitochondrial trans-2-enoyl-CoA reductase).
RGD Description
Enables signaling receptor binding activity. Predicted to be involved in fatty acid metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in childhood-onset dystonia with optic atrophy and basal ganglia abnormalities and optic atrophy. Orthologous to human MECR (mitochondrial trans-2-enoyl-CoA reductase); PARTICIPATES IN fatty acid elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 4-tert-Octylphenol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43981
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
144.030M144.035M144.040M144.045M144.050M144.055M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions