Gene

Adcy2

Species
Rattus norvegicus
Symbol
Adcy2
Name
adenylate cyclase 2
Synonyms
  • AC2
  • adenylate cyclase 2 (brain)
Biotype
protein coding gene
Automated Description
Enables several functions, including G-protein beta/gamma-subunit complex binding activity; adenylate cyclase binding activity; and metal ion binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and cellular response to forskolin. Located in membrane raft and plasma membrane. Part of protein-containing complex. Orthologous to human ADCY2 (adenylate cyclase 2).
RGD Description
Enables several functions, including G-protein beta/gamma-subunit complex binding activity; adenylate cyclase binding activity; and metal ion binding activity. Involved in several processes, including cAMP biosynthetic process; cAMP-mediated signaling; and cellular response to forskolin. Located in membrane raft and plasma membrane. Part of protein-containing complex. Orthologous to human ADCY2 (adenylate cyclase 2); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; endothelin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45627
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
34.40M34.45M34.50M34.55M34.60M34.65M34.70M34.75M34.80M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions