Gene

Gimap5

Species
Rattus norvegicus
Symbol
Gimap5
Name
GTPase, IMAP family member 5
Synonyms
  • GTPase IMAP family member 5
  • IAN-4
Biotype
protein coding gene
Automated Description
Predicted to enable GTP binding activity. Involved in several processes, including negative regulation of metabolic process; positive regulation of lymphocyte mediated immunity; and regulation of T cell activation. Predicted to be located in lysosomal membrane; mitochondrion; and multivesicular body membrane. Used to study lymphopenia and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in portal hypertension. Orthologous to human GIMAP5 (GTPase, IMAP family member 5).
RGD Description
Predicted to enable GTP binding activity. Involved in several processes, including mononuclear cell differentiation; positive regulation of lymphocyte mediated immunity; and regulation of T cell activation. Predicted to be located in lysosomal membrane; mitochondrion; and multivesicular body membrane. Used to study lymphopenia and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in portal hypertension. Orthologous to human GIMAP5 (GTPase, IMAP family member 5); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10903
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
77.688M77.690M77.692M77.694M77.696M77.698M77.700M77.702M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions