Gene

Sostdc1

Species
Rattus norvegicus
Symbol
Sostdc1
Name
sclerostin domain containing 1
Synonyms
  • context-dependent activator and inhibitor of Wnt signalling protein Wise
  • sclerostin domain-containing protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable BMP binding activity and BMP receptor activity. Predicted to be involved in negative regulation of determination of dorsal identity; negative regulation of myoblast differentiation; and negative regulation of signal transduction. Predicted to act upstream of or within several processes, including morphogenesis of an epithelium; negative regulation of canonical Wnt signaling pathway; and odontogenesis of dentin-containing tooth. Predicted to be active in extracellular space. Orthologous to human SOSTDC1 (sclerostin domain containing 1).
RGD Description
Predicted to enable BMP binding activity and BMP receptor activity. Predicted to be involved in negative regulation of determination of dorsal identity; negative regulation of myoblast differentiation; and negative regulation of signal transduction. Predicted to act upstream of or within several processes, including morphogenesis of an epithelium; negative regulation of canonical Wnt signaling pathway; and odontogenesis of dentin-containing tooth. Predicted to be active in extracellular space. Orthologous to human SOSTDC1 (sclerostin domain containing 1); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; Wnt signaling, canonical pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3,7-dihydropurine-6-thione; 4-tert-Octylphenol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14903
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
53.0515M53.0520M53.0525M53.0530M53.0535M53.0540M53.0545M53.0550M53.0555M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions