Enables protein serine/threonine phosphatase inhibitor activity. Involved in cellular response to heat; negative regulation of mRNA catabolic process; and positive regulation of cell cycle process. Located in P-body and nucleus.
SGD Description
Protein required for initiation of the G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylation (S63) by Rim15p increases interaction with and inhibition of PP2A-Cdc55 for timely mitotic progression; can also activate PP2A-Cdc55 complexes and influence Cdc55p localization along with Igo2p; GFP protein localizes to the cytoplasm and nucleus; IGO1 has a paralog, IGO2, that arose from the whole genome duplication