Gene

GSH2

Species
Saccharomyces cerevisiae
Symbol
GSH2
Name
Glutathione
Synonyms
  • YOL049W
Biotype
protein coding gene
Automated Description
Enables glutathione synthase activity. Involved in glutathione biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Used to study Huntington's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; glutathione synthetase deficiency; and glutatione synthetase deficiency with 5-oxoprolinuria. Orthologous to human GSS (glutathione synthetase).
SGD Description
Glutathione synthetase; catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11130:SF0
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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238.8k239.0k239.2k239.4k239.6k239.8k240.0k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions