Gene

rpn-1

Species
Caenorhabditis elegans
Symbol
rpn-1
Name
proteasome Regulatory Particle, Non-ATPase-like 1
Synonyms
  • CELE_T22D1.9
  • T22D1.9
Biotype
protein coding gene
Automated Description
Predicted to enable enzyme regulator activity. Involved in nematode larval development. Predicted to be part of proteasome regulatory particle, base subcomplex. Predicted to be active in nucleus and proteasome storage granule. Orthologous to human PSMD2 (proteasome 26S subunit ubiquitin receptor, non-ATPase 2).
WB Description
rpn-1 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; rpn-1 activity is essential for embryonic, larval, and germline development; by homology, RPN-1 is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10943
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
6.9065M6.9070M6.9075M6.9080M6.9085M6.9090M6.9095M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions