Gene

srp-8

Species
Caenorhabditis elegans
Symbol
srp-8
Name
SeRPin 8
Synonyms
  • CELE_F20D6.3
  • F20D6.3
Biotype
protein coding gene
Automated Description
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); inflammatory bowel disease (multiple); liver disease (multiple); lung disease (multiple); and retinal vascular disease (multiple). Orthologous to several human genes including SERPINB1 (serpin family B member 1); SERPINB10 (serpin family B member 10); and SERPINB11 (serpin family B member 11).
WB Description
srp-8 encodes a predicted serpin (serine protease inhibitor)
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11461
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.1838M8.1840M8.1842M8.1844M8.1846M8.1848M8.1850M8.1852M8.1854M8.1856M8.1858M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions