Gene

hadb-1

Species
Caenorhabditis elegans
Symbol
hadb-1
Name
Hydroxyacyl-CoA Dehydrogenase trifunctional multienzyme complex subunit Beta 1
Synonyms
  • B0303.3
  • CELE_B0303.3
Biotype
protein coding gene
Automated Description
Predicted to enable acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Located in mitochondrion. Is expressed in body wall musculature; hypodermis; intestine; and tail. Human ortholog(s) of this gene implicated in mitochondrial metabolism disease and mitochondrial trifunctional protein deficiency 2. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta).
WB Description
B0303.3 is orthologous to the human gene 3-KETOACYL-COA THIOLASE BETA-SUBUNIT OF TRIFUNCTIONAL PROTEIN (HADHB; OMIM:143450), which when mutated leads to disease.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18919
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.6864M8.6866M8.6868M8.6870M8.6872M8.6874M8.6876M8.6878M8.6880M8.6882M8.6884M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions