Gene

tsen-34

Species
Caenorhabditis elegans
Symbol
tsen-34
Name
Trna (tRNA) Splicing ENdonuclease subunit related 34
Synonyms
  • CELE_K08D10.12
  • K08D10.12
Biotype
protein coding gene
Automated Description
Predicted to enable lyase activity; nucleic acid binding activity; and tRNA-intron endonuclease activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2C. Orthologous to human TSEN34 (tRNA splicing endonuclease subunit 34).
WB Description
K08D10.12 encodes a putative tRNA 3'-site splicing endonuclease subunit, orthologous to human TSEN34 and budding yeast SEN34; K08D10.12 is coexpressed (as is DNJ-15) with the paralogous small nuclear ribonucleoprotein (snRNP)-associated proteins RNP-2/U1A and RNP-3/U2B
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13070
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
4.1785M4.1786M4.1787M4.1788M4.1789M4.1790M4.1791M4.1792M4.1793M4.1794M4.1795M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions