Gene

Y50D7A.3

Species
Caenorhabditis elegans
Symbol
Y50D7A.3
Name
phosphorylase kinase
Synonyms
  • CELE_Y50D7A.3
  • Y50D7A.g
Biotype
protein coding gene
Automated Description
Predicted to enable phosphorylase kinase activity. Predicted to be involved in glycogen metabolic process and signal transduction. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXc; and liver cirrhosis. Orthologous to several human genes including PHKG2 (phosphorylase kinase catalytic subunit gamma 2).
WB Description
Y50D7A.3 is orthologous to human Phosphorylase Kinase Gamma-2 (PHKG2) which is the liver and testis isoform of the gamma subunit of phosphorylase kinase; human PHKG2 phosphorylates and activates glycogen phosphorylase, which leads to the breakdown of glycogen (glycogenolysis).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24347
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
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            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Y50D7A.3 molecule type
            Interactor gene
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              Genetic Interactions

              Y50D7A.3 role
              Y50D7A.3 genetic perturbation
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