Gene

agt

Species
Danio rerio
Symbol
agt
Name
angiotensinogen
Synonyms
  • wu:fb62f06
  • wu:fj87b02
Biotype
protein coding gene
Automated Description
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in regulation of apoptotic process. Predicted to act upstream of or within regulation of systemic arterial blood pressure by renin-angiotensin and vasoconstriction. Predicted to be active in extracellular space. Is expressed in brain; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11461
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
23.989M23.990M23.991M23.992M23.993M23.994M23.995M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions