Gene

pmpca

Species
Danio rerio
Symbol
pmpca
Name
peptidase, mitochondrial processing subunit alpha
Synonyms
  • wu:fi19e06
  • wu:fj83d11
Biotype
protein coding gene
Automated Description
Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to act upstream of or within proteolysis. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; anterior neural keel; head; immature eye; and optic tectum. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 2. Orthologous to human PMPCA (peptidase, mitochondrial processing subunit alpha).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11851
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
65.042M65.044M65.046M65.048M65.050M65.052M65.054M65.056M65.058M65.060M65.062M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions