Gene

phgdh

Species
Danio rerio
Symbol
phgdh
Name
phosphoglycerate dehydrogenase
Synonyms
  • fb38f06
  • wu:fb38f06
Biotype
protein coding gene
Automated Description
Predicted to enable phosphoglycerate dehydrogenase activity. Predicted to act upstream of or within L-serine biosynthetic process. Is expressed in annular ligament. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 1; PHGDH deficiency; and amino acid metabolic disorder. Orthologous to human PHGDH (phosphoglycerate dehydrogenase).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR42938
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
48.190M48.195M48.200M48.205M48.210M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions