Gene

ap4b1

Species
Danio rerio
Symbol
ap4b1
Name
adaptor related protein complex 4 subunit beta 1
Synonyms
  • ap4b1l
  • zgc:63878
Biotype
protein coding gene
Automated Description
Predicted to enable clathrin binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in membrane. Predicted to be part of clathrin adaptor complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 47. Orthologous to human AP4B1 (adaptor related protein complex 4 subunit beta 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11134
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensAP4B110 of 10YesYes  
Mus musculusAp4b110 of 10YesYes  
Rattus norvegicusAp4b19 of 9YesYes   
Xenopus tropicalisap4b19 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
ap1b1172048303 of 8  
ap2b1263652303 of 8  
ap3b1a368543242 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
Homo sapiensAP4B1
is implicated inhereditary spastic paraplegia 47
  • IAGP
    Showing 1 - 1 of 1 rows
    per page

    Alleles and Variants

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    356k358k360k362k364k366ksa9375sa29847ap4b1ap4b1-201ap4b1-202
    Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    sa9375allele with one associated variant
    point mutation
    • splice donor variant
    sa29847allele with one associated variant
    point mutation
    • stop gained
    Showing 1 - 2 of 2 rows
    per page

    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    356k358k360k362k364k366kap4b1-201 (ap4b1)ap4b1-202 (ap4b1)

    Sequence Details

    Transcript: Mode:

    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available