Gene

sp7

Species
Danio rerio
Symbol
sp7
Name
Sp7 transcription factor
Synonyms
  • osterix
  • osx
Biotype
protein coding gene
Automated Description
Enables promoter-specific chromatin binding activity. Involved in positive regulation of gene expression. Acts upstream of or within several processes, including cranial suture morphogenesis; dentinogenesis; and osteoblast differentiation. Is expressed in several structures, including bone element; ectoderm; fin; head; and optic primordium. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23235
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
58.625M58.630M58.635M58.640M58.645M58.650M58.655M58.660M58.665M58.670M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions