Involved in definitive hemopoiesis; digestive system development; and ribosome biogenesis. Acts upstream of or within cartilage morphogenesis and rRNA processing. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including digestive system; eye; immature eye; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).