Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within complement activation and proteolysis. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase).