Gene

sphk2

Species
Danio rerio
Symbol
sphk2
Name
sphingosine kinase 2
Synonyms
  • si:dkey-40m6.13
Biotype
protein coding gene
Automated Description
Predicted to enable D-erythro-sphingosine kinase activity. Acts upstream of or within several processes, including cellular response to ceramide; embryonic viscerocranium morphogenesis; and heart development. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Is expressed in several structures, including blastodisc; heart; liver; pleuroperitoneal region; and yolk syncytial layer. Used to study metabolic dysfunction-associated steatohepatitis. Orthologous to human SPHK2 (sphingosine kinase 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12358
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
32.137M32.138M32.139M32.140M32.141M32.142M32.143M32.144M32.145M32.146M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions