Gene

gba1

Species
Danio rerio
Symbol
gba1
Name
glucosylceramidase beta 1
Synonyms
  • gba
  • gba1
Biotype
protein coding gene
Automated Description
Enables glucosylceramidase activity. Acts upstream of or within several processes, including glucosylceramide catabolic process; swimming; and swimming behavior. Predicted to be located in lysosomal membrane. Is expressed in brain; fertilized egg; fin; liver; and oocyte. Used to study Gaucher's disease. Human ortholog(s) of this gene implicated in Gaucher's disease (multiple); Lewy body dementia; Parkinson's disease (multiple); and Parkinsonism. Orthologous to human GBA1 (glucosylceramidase beta 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11069
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
14.218M14.220M14.222M14.224M14.226M14.228M14.230M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions