Species

Danio rerio

Symbol

slc19a1

Name

solute carrier family 19 member 1

Synonyms

fj80b07
im:7144090

Biotype

protein coding gene

Automated Description

Predicted to enable folate:monoatomic anion antiporter activity and folic acid binding activity. Predicted to be involved in folate transmembrane transport. Predicted to act upstream of or within vitamin transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; cleft lip; dextro-looped transposition of the great arteries; immunodeficiency 114; and malaria. Orthologous to human SLC19A1 (solute carrier family 19 member 1).

ZFIN Description

Not Available

Cross References

Additional Information

Literature

Orthology

Gene tree: Not Available

Stringency:StringentModerateNo filter

Additional filters to further constrain the results:

Best Score OnlyBest Reverse Score Only

Count:Species:Methods:

Species	Gene symbol	Count	Best	Best reverse	Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiens	SLC19A1	9 of 10	Yes	Yes	☐ ☑☑☑☑☑☑☑☑ ☑
Mus musculus	Slc19a1	10 of 10	Yes	Yes	☑ ☑☑☑☑☑☑☑☑ ☑
Rattus norvegicus	Slc19a1	9 of 9	Yes	Yes	☑ ☑☑☑☑☑☑☑☑
Xenopus tropicalis	slc19a1	9 of 9	Yes	Yes	☑ ☑☑☑☑☑☑☑☑
Drosophila melanogaster	CG14694	9 of 10	Yes	Yes	☑ ☑☑☑☑☑☑☑☑ ☐
Drosophila melanogaster	CG17036	9 of 10	Yes	Yes	☑ ☑☑☑☑☑☑☑☑ ☐
Drosophila melanogaster	CG6574	9 of 10	Yes	Yes	☑ ☑☑☑☑☑☑☑☑ ☐
Caenorhabditis elegans	folt-2	7 of 9	Yes	Yes	☑ ☑☐☑☑☐☑☑☑
Caenorhabditis elegans	folt-1	7 of 9	Yes	No	☑ ☑☐☑☑☐☑☑☑
Caenorhabditis elegans	folt-3	7 of 9	Yes	Yes	☑ ☑☐☑☑☐☑☑☑

Paralogy

Gene symbol	Rank	Alignment Length (aa)	Similarity %	Identity %	Method Count	Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
slc19a3b	1	480	56	35	6 of 8	☑ ☑☐☐☑☑☑☑
slc19a3a	2	489	53	37	6 of 8	☑ ☑☐☐☑☑☑☑
slc19a2	3	468	56	37	6 of 8	☑ ☑☐☐☑☑☑☑

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

No data available

Disease Associations

Must provide at least one subject

Cell color indicative of annotation volume

No data available

Alleles and Variants

Allele/Variant Symbol	Allele Synonyms	Category	Variant	Variant type	Molecular consequence	Has Disease Annotations	Has Phenotype Annotations
sa40675		allele with one associated variant	NC_007117.7:g.20669943A>G point mutation splice acceptor variant

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Transgenic Alleles

No data available

Models

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Sequence Feature Viewer

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Sequence Details

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Expression

Primary Sources

None

Other Sources

Must provide at least one subject

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available