Gene

smpd1

Species
Danio rerio
Symbol
smpd1
Name
sphingomyelin phosphodiesterase 1
Synonyms
  • si:ch211-287a12.10
Biotype
protein coding gene
Automated Description
Predicted to enable hydrolase activity, acting on glycosyl bonds; metal ion binding activity; and sphingomyelin phosphodiesterase activity. Acts upstream of or within lipid metabolic process and respiratory electron transport chain. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in Niemann-Pick disease; Niemann-Pick disease type A; and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10340
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
24.710M24.712M24.714M24.716M24.718M24.720M24.722M24.724M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions