Predicted to enable methylated-DNA-[protein]-cysteine S-methyltransferase activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within DNA damage response and methylation. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); granulosa cell tumor; high grade glioma (multiple); and retinoblastoma. Orthologous to human MGMT (O-6-methylguanine-DNA methyltransferase).