Gene

pgfb

Species
Danio rerio
Symbol
pgfb
Name
placental growth factor b
Synonyms
  • si:dkey-204k5.1
  • zmp:0000000808
Biotype
protein coding gene
Automated Description
Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of chemotaxis; and sprouting angiogenesis. Predicted to be located in membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12025
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
44.700M44.705M44.710M44.715M44.720M44.725M44.730M44.735M44.740M44.745M44.750M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions