Gene

tfa

Species
Danio rerio
Symbol
tfa
Name
transferrin-a
Synonyms
  • cb285
  • gavi
Biotype
protein coding gene
Automated Description
Predicted to enable metal ion binding activity. Acts upstream of or within hemoglobin biosynthetic process; iron ion transport; and response to bacterium. Predicted to be located in extracellular region. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in several structures, including ball; liver; ovary; renal system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); atransferrinemia; carcinoma (multiple); glucose metabolism disease (multiple); and restless legs syndrome. Orthologous to human LTF (lactotransferrin) and TF (transferrin).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11485
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
16.782M16.784M16.786M16.788M16.790M16.792M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions