Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: A2M (Hsa)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: A2M (Hsa)
Disease
Source: DOID:0080600
Definition: A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.
Genes: A2M (Hsa)
Disease
Source: DOID:114
Definition: A cardiovascular system disease that involves the heart.
Genes: A2M (Hsa)
Disease
Source: DOID:14330
Definition: A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Genes: A2M (Hsa)
Disease
Source: DOID:2377
Definition: A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Genes: A2M (Hsa)
Disease
Source: DOID:684
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.
Genes: A2M (Hsa)
Disease
Source: DOID:1184
Definition: A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Genes: A2M (Hsa)
Disease
Source: DOID:3526
Definition: A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.
Genes: A2M (Hsa)
Disease
Source: DOID:583
Definition: A normocytic anemia that is characterized by the rate of descruction of red blood cells exceeding the rate than they can be made.
Genes: A2M (Hsa)
Disease
Source: DOID:14115
Definition: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
Genes: A2M (Hsa)
Disease
Source: DOID:2320
Definition: A lung disease that is characterized by narrowing of pulmonary airways.
Genes: A2M (Hsa)
Disease
Source: DOID:0050868
Definition: A liver benign neoplasm that is located_in liver cells and that is composed_of epithelial tissue in which tumor cells form glands or glandlike structures.
Genes: A2M (Hsa)
Disease
Source: DOID:8283
Definition: A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.
Genes: A2M (Hsa)
Disease
Source: DOID:10159
Definition: An ischemic bone disease that results_in necrosis located_in bone.
Genes: A2M (Hsa)
Disease
Source: DOID:10113
Definition: A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.
Genes: A2M (Hsa)