Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: ADAM10 (Hsa)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:0050700
Definition: A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:83
Definition: A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:9256
Definition: A large intestine cancer that is located_in the colon and/or located_in the rectum.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:14004
Definition: An aortic aneurysm that is located_in the thoracic aorta.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:0110050
Definition: An Alzheimer's disease that has_material_basis_in a mutation in the ADAM10 gene on chromosome 15q21.
Genes: ADAM10 (Hsa)
Disease
Source: DOID:0081292
Definition: A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.
Genes: ADAM10 (Hsa)
Source: DOID:0060258
Definition: A pigmentation disease characterized by lesions that initially arise as letiginous, hyperpigmented macules in a reticular pattern on the dorsal aspect of the hands and feet. Over time, lesions may spread proximally and may darken; palmoplantar pitting and dermatoglyphic disruption may also be present.
Genes: ADAM10 (Hsa)