Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: E2f1 (Dme)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: E2f1 (Dme)
Disease
Source: DOID:9744
Definition: A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Genes: E2f1 (Dme)
Disease
Source: DOID:1793
Definition: An endocrine gland cancer located_in the pancreas.
Genes: E2f1 (Dme)
Disease
Source: DOID:12858
Definition: A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.
Genes: E2f1 (Dme)
Disease
Source: DOID:10283
Definition: A male reproductive organ cancer that is located_in the prostate.
Genes: E2f1 (Dme)
Disease
Source: DOID:11054
Definition: An urinary system cancer that results_in malignant growth located_in the urinary bladder.
Genes: E2f1 (Dme)
Disease
Source: DOID:3347
Definition: A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).
Genes: E2f1 (Dme)
Disease
Source: DOID:3068
Definition: A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Genes: E2f1 (Dme)
Disease
Source: DOID:8552
Definition: A myeloid leukemia that is characterized by over production of white blood cells.
Genes: E2f1 (Dme)
Disease
Source: DOID:3910
Definition: A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.
Genes: E2f1 (Dme)
Source: DOID:3908
Definition: A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
Genes: E2f1 (Dme)
Disease
Source: DOID:3070
Definition: A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.
Genes: E2f1 (Dme)
Disease
Source: DOID:1307
Definition: A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.
Genes: E2f1 (Dme)
Disease
Source: DOID:12894
Definition: An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Genes: E2f1 (Dme)
Disease
Source: DOID:4074
Definition: A pancreatic carcinoma that derives_from epithelial cells of glandular origin.
Genes: E2f1 (Dme)
Disease
Source: DOID:5409
Definition: A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.
Genes: E2f1 (Dme)
Source: DOID:3498
Definition: A pancreatic adenocarcinoma that derives_from pancreatic duct cells.
Genes: E2f1 (Dme)
Disease
Source: DOID:3907
Definition: A non-small cell lung carcinoma that has_material_basis_in the squamous cell.
Genes: E2f1 (Dme)
Disease
Source: DOID:646
Definition: An encephalitis that involves inflammation of the brain caused by viral infection.
Genes: E2f1 (Dme)