Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: FTO (Hsa)
Disease
Source: DOID:9352
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Genes: FTO (Hsa)
Disease
Source: DOID:6000
Definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.
Genes: FTO (Hsa)
Disease
Source: DOID:9970
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Genes: FTO (Hsa)
Disease
Source: DOID:10763
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries.
Genes: FTO (Hsa)
Source: DOID:0080208
Definition: A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.
Genes: FTO (Hsa)
Disease
Source: DOID:3393
Definition: An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.
Genes: FTO (Hsa)
Source: DOID:1287
Definition: A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
Genes: FTO (Hsa)
Disease
Source: DOID:224
Definition: A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.
Genes: FTO (Hsa)
Disease
Source: DOID:9477
Definition: An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.
Genes: FTO (Hsa)
Disease
Source: DOID:5844
Definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.
Genes: FTO (Hsa)
Disease
Source: DOID:10825
Definition: A hypertension with no known cause. It is the most common type of hypertension.
Genes: FTO (Hsa)
Disease
Source: DOID:7693
Definition: An aortic aneurysm that is located_in the abdominal aorta.
Genes: FTO (Hsa)
Disease
Source: DOID:9538
Definition: A myeloid neoplasm that is located_in the plasma cells in bone marrow.
Genes: FTO (Hsa)
Disease
Source: DOID:0080334
Definition: A bicuspid aortic valve disease that has_material_basis_in heterozygous mutation in the SMAD6 gene on chromosome 15q22.
Genes: FTO (Hsa)
Disease
Source: DOID:4450
Definition: A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.
Genes: FTO (Hsa)
Source: DOID:4467
Definition: A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.
Genes: FTO (Hsa)
Disease
Source: DOID:13963
Definition: A senile cataract that is characterized by opacification of the lens nucleus and caused by changes related to aging.
Genes: FTO (Hsa)
Disease
Source: DOID:0081292
Definition: A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.
Genes: FTO (Hsa)