Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: H2-T22 (Mmu)
Disease
Source: DOID:0080600
Definition: A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:2841
Definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:6039
Definition: A uveal cancer that has_material_basis_in uvea pigment cells.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:9849
Definition: A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:988
Definition: A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.
Genes: H2-T22 (Mmu)
Source: DOID:2945
Definition: A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:4362
Definition: A female reproductive organ cancer that is located_in the cervix.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:1485
Definition: A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:13241
Definition: A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:9415
Definition: An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:399
Definition: A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:7147
Definition: An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0060180
Definition: An inflammatory bowel disease that involves inflammation located_in colon.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:13141
Definition: An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:3526
Definition: A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.
Genes: H2-T22 (Mmu)
Source: DOID:526
Definition: A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:2723
Definition: A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0111079
Definition: A posterior uveitis characterized by multiple small, hypopigmented, cream-colored choroidal lesions scattered symmetrically in the fundus primarily around the optic disc that presents in patients as blurred vision, floaters, photopsia, scotoma and nyctalopia.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:2508
Definition: A vasculitis that involves inflammation of the aorta that carries blood from the heart to the rest of the body.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:10003
Definition: An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:4481
Definition: A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:11335
Definition: A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:1883
Definition: A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepacivirus hominis, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:11563
Definition: A vasculitis that is characterized by inflammation of the vascular branches of the retinal artery and has_symptom painless decrease of visual acuity, visual floaters, dark spot in vision, decreased ability to distinguish colors, and distortion of images such as linear images.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:12185
Definition: An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.
Genes: H2-T22 (Mmu)
Source: DOID:1273
Definition: A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus, which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0080750
Definition: A panniculitis that is characterized by sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0080820
Definition: An environmental induced asthma that is characterized by a variable airflow limitation due to exposure to inhaled irritants in the workplace.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0080160
Definition: A retinitis that has_material_basis_in Cytomegalovirus.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0050426
Definition: A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:2703
Definition: A connective tissue disease that results_in inflammation located_in synovial membrane that lines a synovial joint which causes pain and swelling.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:3875
Definition: A phlebitis that results from a blood clot in the vessel.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:11265
Definition: A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:6196
Definition: An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:987
Definition: A hypotrichosis that is characterized by a loss of hair from the head or body.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:0111286
Definition: A psoriasis that has_material_basis_in variation in HLA-C on chromosome 6p21.33.
Genes: H2-T22 (Mmu)
Disease
Source: DOID:12361
Definition: An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.
Genes: H2-T22 (Mmu)
Source: DOID:3611
Definition: Not Available
Genes: H2-T22 (Mmu)