Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: Il4 (Rno)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: Il4 (Rno)
Disease
Source: DOID:0080600
Definition: A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.
Genes: Il4 (Rno)
Disease
Source: DOID:2841
Definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Genes: Il4 (Rno)
Disease
Source: DOID:9744
Definition: A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Genes: Il4 (Rno)
Disease
Source: DOID:1793
Definition: An endocrine gland cancer located_in the pancreas.
Genes: Il4 (Rno)
Disease
Source: DOID:3310
Definition: An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.
Genes: Il4 (Rno)
Disease
Source: DOID:2377
Definition: A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Genes: Il4 (Rno)
Disease
Source: DOID:13241
Definition: A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.
Genes: Il4 (Rno)
Disease
Source: DOID:1561
Definition: A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.
Genes: Il4 (Rno)
Disease
Source: DOID:8893
Definition: A skin disease that is characterized by patches of thick red skin and silvery scales.
Genes: Il4 (Rno)
Disease
Source: DOID:1459
Definition: A thyroid gland disease which involves an underproduction of thyroid hormone.
Genes: Il4 (Rno)
Disease
Source: DOID:1184
Definition: A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Genes: Il4 (Rno)
Disease
Source: DOID:10223
Definition: A myositis that results_in inflammation located_in muscle or located_in skin where a skin rash is often seen prior to the onset of muscle weakness. The disease may result from either a viral infection or an autoimmune reaction.
Genes: Il4 (Rno)
Disease
Source: DOID:418
Definition: A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Genes: Il4 (Rno)
Source: DOID:0050625
Definition: A hepatobiliary benign neoplasm located_in the biliary tract.
Genes: Il4 (Rno)
Disease
Source: DOID:2048
Definition: An autoimmune disease of gastrointestinal tract that results_in inflammation located_in liver caused by the body's immune system attacking the liver cells.
Genes: Il4 (Rno)
Disease
Source: DOID:3770
Definition: An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.
Genes: Il4 (Rno)
Disease
Source: DOID:12306
Definition: An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.
Genes: Il4 (Rno)
Disease
Source: DOID:4483
Definition: A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.
Genes: Il4 (Rno)
Disease
Source: DOID:7188
Definition: An autoimmune disease of endocrine system that involves inflammation located_in thyroid gland caused by the immune system reacting against its own tissues.
Genes: Il4 (Rno)
Disease
Source: DOID:2043
Definition: A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.
Genes: Il4 (Rno)
Disease
Source: DOID:8536
Definition: A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia.
Genes: Il4 (Rno)
Disease
Source: DOID:4481
Definition: A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.
Genes: Il4 (Rno)
Disease
Source: DOID:12894
Definition: An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Genes: Il4 (Rno)
Disease
Source: DOID:1883
Definition: A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepacivirus hominis, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.
Genes: Il4 (Rno)
Disease
Source: DOID:12236
Definition: A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.
Genes: Il4 (Rno)
Disease
Source: DOID:3587
Definition: A pancreatic carcinoma located_in the pancreatic duct.
Genes: Il4 (Rno)
Disease
Source: DOID:1679
Definition: A bladder disease that is characterized by inflammation of the bladder.
Genes: Il4 (Rno)
Disease
Source: DOID:13375
Definition: A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head.
Genes: Il4 (Rno)
Disease
Source: DOID:2772
Definition: A contact dermatitis that is characterized by a cutaneous inflammatory reaction to repeated contact with an irritant substance, friction, liquid, or adverse temperature that interacts with the skin and often has_symptom erythema, edema, scaling, pain, pruritis, or burning sensation.
Genes: Il4 (Rno)
Disease
Source: DOID:13580
Definition: A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.
Genes: Il4 (Rno)
Disease
Source: DOID:10952
Definition: A kidney disease that is characterized by an inflammation of the kidneys.
Genes: Il4 (Rno)
Source: DOID:8924
Definition: A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.
Genes: Il4 (Rno)
Disease
Source: DOID:1003
Definition: A female reproductive system disease that is characterized by an infection of the female reproductive organs.
Genes: Il4 (Rno)
Source: DOID:0060061
Definition: A peripheral T-cell lymphoma that has_material_basis_in a mutation of T cells.
Genes: Il4 (Rno)
Disease
Source: DOID:9790
Definition: A parasitic helminthiasis infectious disease that involves zoonotic infection of humans by the larvae of Toxocara canis or Toxocara cati. The larvae invade multiple tissues like liver, heart, lungs, brain, muscle and eyes causing various symptoms including fever, anorexia, weight loss, cough, wheezing, rashes, hepatosplenomegaly, hypereosinophilia and ophthalmologic lesions.
Genes: Il4 (Rno)
Disease
Source: DOID:1495
Definition: An echinococcosis that is caused by the larvae of Echinococcus granulosus. Hepatic involvement can result in abdominal pain, a mass in the hepatic area, and biliary duct obstruction. Pulmonary involvement can produce chest pain, cough, and hemoptysis. Rupture of the cysts produce fever, urticaria, eosinophilia, and anaphylactic shock, as well as cyst dissemination. Brain, bone, heart can also be infected.
Genes: Il4 (Rno)
Source: DOID:0080822
Definition: An intrinsic asthma that is characterized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.
Genes: Il4 (Rno)
Disease
Source: DOID:2799
Definition: A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.
Genes: Il4 (Rno)
Disease
Source: DOID:9065
Definition: A parasitic protozoa infectious disease that involves infection caused by protozoan parasite of the genus Leishmania, which is transmitted by the bite of sand fly (subfamily Phlebotominae).
Genes: Il4 (Rno)
Disease
Source: DOID:0050634
Definition: An alopecia characterized by the complete loss of hair on the scalp and body.
Genes: Il4 (Rno)
Disease
Source: DOID:10113
Definition: A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.
Genes: Il4 (Rno)
Source: DOID:4780
Definition: A Goodpasture syndrome that is characterized by damage to only kidney capillaries.
Genes: Il4 (Rno)
Disease
Source: DOID:11168
Definition: A viral infectious disease that results_in infection located_in skin of vagina, cervix, uterus, anus, penis, scrotum, mouth, or throat, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during oral, genital, or anal sex with an infected partner. The infection has_symptom anogenital warts.
Genes: Il4 (Rno)
Disease
Source: DOID:0080745
Definition: A myositis that is characterized by muscle weakness affecting both sides of your body.
Genes: Il4 (Rno)