Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: MRE11 (Hsa)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: MRE11 (Hsa)
Disease
Source: DOID:1612
Definition: An organ system cancer that originates in the mammary gland.
Genes: MRE11 (Hsa)
Disease
Source: DOID:2394
Definition: A female reproductive organ cancer that is located_in the ovary.
Genes: MRE11 (Hsa)
Disease
Source: DOID:219
Definition: A colorectal cancer that is located_in the colon.
Genes: MRE11 (Hsa)
Disease
Source: DOID:11054
Definition: An urinary system cancer that results_in malignant growth located_in the urinary bladder.
Genes: MRE11 (Hsa)
Disease
Source: DOID:3571
Definition: A hepatobiliary system cancer that is located_in the liver.
Genes: MRE11 (Hsa)
Disease
Source: DOID:4159
Definition: An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.
Genes: MRE11 (Hsa)
Disease
Source: DOID:3459
Definition: A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
Genes: MRE11 (Hsa)
Disease
Source: DOID:1380
Definition: A uterine cancer that is located_in tissues lining the uterus.
Genes: MRE11 (Hsa)
Disease
Source: DOID:3069
Definition: A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.
Genes: MRE11 (Hsa)
Disease
Source: DOID:3883
Definition: A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.
Genes: MRE11 (Hsa)
Disease
Source: DOID:10155
Definition: A gastrointestinal system cancer that is located_in the intestine.
Genes: MRE11 (Hsa)
Disease
Source: DOID:1993
Definition: A colorectal cancer that is located_in the rectum.
Genes: MRE11 (Hsa)
Disease
Source: DOID:5517
Definition: A stomach cancer that is located_in the stomach.
Genes: MRE11 (Hsa)
Source: DOID:0081384
Definition: An autosomal recessive cerebellar ataxia that is characterized clinically by progressive cerebellar degeneration resulting in ataxia and oculomotor apraxia and that has_material_basis_in homozygous or compound heterozygous mutation in the MRE11A gene (MRE11) on chromosome 11q21.
Genes: MRE11 (Hsa)