Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: Notch1 (Rno)
Disease
Source: DOID:162
Definition: A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
Genes: Notch1 (Rno)
Disease
Source: DOID:9970
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Genes: Notch1 (Rno)
Disease
Source: DOID:1319
Definition: A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.
Genes: Notch1 (Rno)
Disease
Source: DOID:1380
Definition: A uterine cancer that is located_in tissues lining the uterus.
Genes: Notch1 (Rno)
Disease
Source: DOID:4947
Definition: A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.
Genes: Notch1 (Rno)
Disease
Source: DOID:224
Definition: A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.
Genes: Notch1 (Rno)
Disease
Source: DOID:9256
Definition: A large intestine cancer that is located_in the colon and/or located_in the rectum.
Genes: Notch1 (Rno)
Disease
Source: DOID:3910
Definition: A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.
Genes: Notch1 (Rno)
Source: DOID:3620
Definition: A nervous system cancer that is located_in the central nervous system.
Genes: Notch1 (Rno)
Disease
Source: DOID:3770
Definition: An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.
Genes: Notch1 (Rno)
Disease
Source: DOID:299
Definition: A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.
Genes: Notch1 (Rno)
Disease
Source: DOID:0060227
Definition: A syndrome characterized by defects of the scalp (aplasia cutis congenita), abnormalities of the fingers, toes, arms and legs.
Genes: Notch1 (Rno)
Disease
Source: DOID:10155
Definition: A gastrointestinal system cancer that is located_in the intestine.
Genes: Notch1 (Rno)
Disease
Source: DOID:1574
Definition: A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.
Genes: Notch1 (Rno)
Disease
Source: DOID:5409
Definition: A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.
Genes: Notch1 (Rno)
Source: DOID:0050523
Definition: A T-cell acute leukemia that results_in abnormal increase of lymphocytes, derives_from T-cells, has_material_basis_in Human T-lymphotropic virus 1 (HTLV-1), which is transmitted_by sexual contact, transmitted_by contaminated needles used by intravenous-drug users, and transmitted_by breast feeding. The infection results_in_formation_of skin lesions.
Genes: Notch1 (Rno)
Disease
Source: DOID:0080333
Definition: A bicuspid aortic valve disease that has_material_basis_in heterozygous mutation in the NOTCH1 gene on chromosome 9q34.
Genes: Notch1 (Rno)
Disease
Source: DOID:264
Definition: A hemangiopericytic tumor that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.
Genes: Notch1 (Rno)