Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: TIMP1 (Hsa)
Disease
Source: DOID:114
Definition: A cardiovascular system disease that involves the heart.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:9352
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:1612
Definition: An organ system cancer that originates in the mammary gland.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:6000
Definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:9351
Definition: A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:14250
Definition: A chromosomal disease that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:9744
Definition: A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:2394
Definition: A female reproductive organ cancer that is located_in the ovary.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:9970
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:10763
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:1485
Definition: A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:10588
Definition: A leukodystrophy that disrupts the breakdown of very-long-chain fatty acids resulting in progressive brain damage, failure of the adrenal glands and eventually death.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:178
Definition: A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:10591
Definition: A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:14004
Definition: An aortic aneurysm that is located_in the thoracic aorta.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:2871
Definition: A endometrial cancer that is located_in the tissue lining the uterus.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:3770
Definition: An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.
Genes: TIMP1 (Hsa)
Source: DOID:2378
Definition: A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:13378
Definition: A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and inflammation of medium-sized blood vessels and that symptoms of fever, congestion of ocular conjunctivae, reddening of lips, reddening of oral cavity, protuberance of tongue papillae and edema of extremities.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:90
Definition: A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:4450
Definition: A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.
Genes: TIMP1 (Hsa)
Source: DOID:3083
Definition: An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:2671
Definition: A carcinoma that derives_from transitional epithelial cells.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:13580
Definition: A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.
Genes: TIMP1 (Hsa)
Disease
Source: DOID:0080207
Definition: A CAKUT that has_material_basis_in heterozygous mutation in the TBX18 gene on chromosome 6q14.
Genes: TIMP1 (Hsa)
Source: DOID:0080547
Definition: A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.
Genes: TIMP1 (Hsa)