Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: sod2.S (Xla)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: sod2.S (Xla)
Disease
Source: DOID:2841
Definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Genes: sod2.S (Xla)
Disease
Source: DOID:9352
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Genes: sod2.S (Xla)
Disease
Source: DOID:1612
Definition: An organ system cancer that originates in the mammary gland.
Genes: sod2.S (Xla)
Disease
Source: DOID:9074
Definition: A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
Genes: sod2.S (Xla)
Disease
Source: DOID:9744
Definition: A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Genes: sod2.S (Xla)
Disease
Source: DOID:1793
Definition: An endocrine gland cancer located_in the pancreas.
Genes: sod2.S (Xla)
Disease
Source: DOID:2394
Definition: A female reproductive organ cancer that is located_in the ovary.
Genes: sod2.S (Xla)
Disease
Source: DOID:1324
Definition: A respiratory system cancer that is located_in the lung.
Genes: sod2.S (Xla)
Disease
Source: DOID:0050700
Definition: A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.
Genes: sod2.S (Xla)
Disease
Source: DOID:10763
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries.
Genes: sod2.S (Xla)
Source: DOID:0080208
Definition: A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.
Genes: sod2.S (Xla)
Disease
Source: DOID:11054
Definition: An urinary system cancer that results_in malignant growth located_in the urinary bladder.
Genes: sod2.S (Xla)
Disease
Source: DOID:1909
Definition: A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.
Genes: sod2.S (Xla)
Disease
Source: DOID:9119
Definition: A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
Genes: sod2.S (Xla)
Disease
Source: DOID:1070
Definition: An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.
Genes: sod2.S (Xla)
Disease
Source: DOID:12930
Definition: An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.
Genes: sod2.S (Xla)
Disease
Source: DOID:8893
Definition: A skin disease that is characterized by patches of thick red skin and silvery scales.
Genes: sod2.S (Xla)
Disease
Source: DOID:10534
Definition: A gastrointestinal system cancer that is located_in the stomach.
Genes: sod2.S (Xla)
Disease
Source: DOID:684
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.
Genes: sod2.S (Xla)
Disease
Source: DOID:1184
Definition: A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Genes: sod2.S (Xla)
Disease
Source: DOID:5844
Definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.
Genes: sod2.S (Xla)
Disease
Source: DOID:13641
Definition: A phacogenic glaucoma that is characterized by open-angle glaucoma related to deposition of extracellular fibrillar material in anterior segment structures, which blocks aqueous fluid outflow, raises intraocular pressure, and leads to eventual optic nerve atrophy and visual field loss. Exfoliation syndrome has_symptom progressive decreased vision, especially peripheral vision. Exfoliation syndrome is caused by age-related deposition of fibrillar material in anterior segment structures.
Genes: sod2.S (Xla)
Source: DOID:14503
Definition: Not Available
Genes: sod2.S (Xla)
Disease
Source: DOID:11476
Definition: A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Genes: sod2.S (Xla)
Disease
Source: DOID:12306
Definition: An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.
Genes: sod2.S (Xla)
Disease
Source: DOID:9538
Definition: A myeloid neoplasm that is located_in the plasma cells in bone marrow.
Genes: sod2.S (Xla)
Disease
Source: DOID:2741
Definition: An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.
Genes: sod2.S (Xla)
Disease
Source: DOID:12236
Definition: A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.
Genes: sod2.S (Xla)
Disease
Source: DOID:4724
Definition: A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma.
Genes: sod2.S (Xla)
Source: DOID:705
Definition: Not Available
Genes: sod2.S (Xla)
Disease
Source: DOID:3429
Definition: A myositis that is characterized by late onset of skeletal muscle inflammation, weakness, and atrophy with cytoplasmic granules and vacuoles in the muscle.
Genes: sod2.S (Xla)
Source: DOID:0080547
Definition: A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.
Genes: sod2.S (Xla)
Disease
Source: DOID:1210
Definition: An optic nerve disease that results_in inflammation located_in optic nerve which may cause a complete or partial loss of vision.
Genes: sod2.S (Xla)
Disease
Source: DOID:6196
Definition: An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.
Genes: sod2.S (Xla)
Disease
Source: DOID:11713
Definition: A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.
Genes: sod2.S (Xla)
Disease
Source: DOID:1555
Definition: A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis.
Genes: sod2.S (Xla)
Disease
Source: DOID:8568
Definition: A viral infectious disease that results in inflammation, located in pharynx, has_material_basis_in Human herpesvirus 4 and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.
Genes: sod2.S (Xla)
Disease
Source: DOID:1389
Definition: A peripheral system disease that is characterized by damage affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, pins-and-needles, and burning pain.
Genes: sod2.S (Xla)
Disease
Source: DOID:2738
Definition: A connective tissue disease that is characterized by the accumulation of deposits of calcium and other minerals in elastic fibers, which are a component of connective tissue, this can result in changes in the skin, eyes, cardiovascular system and gastrointestinal system.
Genes: sod2.S (Xla)