Version: 8.0.0Date: Tue Jan 28 2025
Disease Genes: tau (Dme)
Disease
Source: DOID:10652
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Genes: tau (Dme)
Disease
Source: DOID:1612
Definition: An organ system cancer that originates in the mammary gland.
Genes: tau (Dme)
Disease
Source: DOID:14330
Definition: A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Genes: tau (Dme)
Disease
Source: DOID:1826
Definition: A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.
Genes: tau (Dme)
Source: DOID:332
Definition: A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
Genes: tau (Dme)
Disease
Source: DOID:9970
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Genes: tau (Dme)
Disease
Source: DOID:1289
Definition: A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Genes: tau (Dme)
Disease
Source: DOID:1561
Definition: A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.
Genes: tau (Dme)
Disease
Source: DOID:680
Definition: A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.
Genes: tau (Dme)
Disease
Source: DOID:3328
Definition: A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.
Genes: tau (Dme)
Source: DOID:0060892
Definition: A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.
Genes: tau (Dme)
Disease
Source: DOID:1307
Definition: A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.
Genes: tau (Dme)
Disease
Source: DOID:9255
Definition: A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.
Genes: tau (Dme)
Disease
Source: DOID:11870
Definition: A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.
Genes: tau (Dme)
Source: DOID:678
Definition: A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.
Genes: tau (Dme)
Disease
Source: DOID:8725
Definition: A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.
Genes: tau (Dme)
Disease
Source: DOID:2316
Definition: An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.
Genes: tau (Dme)
Disease
Source: DOID:10914
Definition: A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.
Genes: tau (Dme)
Disease
Source: DOID:0080855
Definition: A movement disorder that is characterized by disturbances of balance, gait and posture.
Genes: tau (Dme)
Disease
Source: DOID:0081292
Definition: A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.
Genes: tau (Dme)