Version: 8.0.0Date: Tue Jan 28 2025
Disease
Disease
Source: DOID:0111981
Definition: A primary immunodeficiency disease characterized by recurrent infections, reduced serum concentrations of immunoglobulin G and albumin due to rapid degradation of these proteins, abnormal renal or liver function, and excessive gastrointestinal protein that has_material_basis_in homozygous or compound heterozygous mutation in B2M on chromosome 15q21.1.
Genes: b2ml (Dre)...B2m (Mmu)...b2m (Dre)...b2m (Xtr)...B2m (Rno)
Synonyms: B2M deficiency
Disease
Source: DOID:8622
Definition: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom fever, has_symptom cough, has_symptom coryza, has_symptom conjunctivitis, and has_symptom maculopapular, erythematous rash.
Genes: b2ml (Dre)...B2m (Mmu)...b2m (Dre)...b2m (Xtr)...B2m (Rno)
Disease
Source: DOID:640
Definition: Not Available
Genes: b2ml (Dre)...B2m (Mmu)...B2m (Rno)...B2M (Hsa)...b2m (Dre)
Disease
Source: DOID:0060704
Definition: A primary immunodeficiency disease characterized by immune dysregulation typically after viral infection, usually associated with Epstein-Barr viral infection.
Genes: B2m (Mmu)...b2m (Xtr)...b2m (Dre)...b2m.S (Xla)...B2m (Rno)
Disease
Source: DOID:848
Definition: A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint.
Genes: B2m (Mmu)...b2m (Xtr)...b2m (Dre)...b2m.S (Xla)...B2m (Rno)
Disease
Source: DOID:2352
Definition: A metal metabolism disorder characterized by the accumulation of iron in various organs of the body.
Genes: B2m (Mmu)...b2m (Xtr)...b2m (Dre)...B2m (Rno)...B2M (Hsa)
Alleles: B2m
Disease
Source: DOID:417
Definition: An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.
Genes: B2m (Mmu)...b2m (Dre)...b2ml (Dre)...B2M (Hsa)...b2m (Xtr)
Disease
Source: DOID:0050830
Definition: An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs.
Genes: B2m (Mmu)...b2m (Xtr)...b2m (Dre)...b2m.S (Xla)...B2m (Rno)
Disease
Source: DOID:11400
Definition: Not Available
Genes: B2m (Mmu)...b2m (Dre)...b2m (Xtr)...B2m (Rno)...B2M (Hsa)
Disease
Source: DOID:3407
Definition: Not Available
Genes: B2m (Mmu)...b2ml (Dre)...b2m (Dre)...B2M (Hsa)...b2m (Xtr)
Disease
Source: DOID:0050589
Definition: An intestinal disease characterized by inflammation located in all parts of digestive tract.
Genes: b2m.S (Xla)...b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)
Disease
Source: DOID:576
Definition: A kidney disease that is characterized by the presence of excess proteins in the urine.
Genes: B2m (Mmu)...b2ml (Dre)...b2m (Dre)...B2M (Hsa)...b2m (Xtr)
Disease
Source: DOID:5199
Definition: An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.
Genes: b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)...B2m (Rno)
Disease
Source: DOID:9538
Definition: A myeloid neoplasm that is located_in the plasma cells in bone marrow.
Genes: b2m.S (Xla)...b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)
Disease
Source: DOID:2349
Definition: An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.
Genes: b2m.S (Xla)...b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)
Disease
Source: DOID:83
Definition: A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.
Genes: b2m.S (Xla)...b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)
Disease
Source: DOID:3021
Definition: Not Available
Genes: b2m (Dre)...b2m (Xtr)...B2m (Mmu)...B2M (Hsa)...B2m (Rno)
Disease
Source: DOID:14330
Definition: A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Genes: b2m.S (Xla)...b2m (Dre)...b2m (Xtr)...B2m (Mmu)...b2ml (Dre)
Disease
Source: DOID:9352
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Genes: B2m (Mmu)...b2ml (Dre)...B2M (Hsa)...B2m (Rno)...b2m (Dre)
Disease
Source: DOID:9970
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Genes: B2m (Mmu)...b2ml (Dre)...B2M (Hsa)...B2m (Rno)...b2m (Dre)
Disease
Source: DOID:10763
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries.
Genes: B2m (Mmu)...b2ml (Dre)...B2M (Hsa)...B2m (Rno)...b2m (Dre)