Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: lung non-small cell carcinoma Molecular Function: small molecule binding
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
STAT5B
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 5B
Synonyms: transcription factor STAT5B, STAT5, GHISID2
Source: HGNC:11367
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, bHLHe39, MRTL, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
Ttr
(Mus musculus)Gene
Name: transthyretin
Synonyms: TT, expressed sequence AA408768, AA408768, prealbumin, expressed sequence AI787086, expressed sequence D17860, Tbpa, Lr1, AI787086, D17860
Source: MGI:98865
Biotype: protein coding gene
Mir223
(Mus musculus)Gene
Name: microRNA 223
Synonyms: miR-223, mmu-mir-223, Mirn223
Source: MGI:2684360
Biotype: miRNA gene
aap-1
(Caenorhabditis elegans)Gene
Name: phosphoinositide kinase AdAPter subunit 1
Synonyms: CELE_Y110A7A.10, Y110A7A.10
Source: WB:WBGene00000001
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
ttr
(Danio rerio)Gene
Name: transthyretin (prealbumin, amyloidosis type I)
Synonyms: zgc:103583
Source: ZFIN:ZDB-GENE-040927-14
Biotype: protein coding gene
CDKN1B
(Homo sapiens)Gene
Name: cyclin dependent kinase inhibitor 1B
Synonyms: CDKN4, cyclin-dependent kinase inhibitor 1B, MEN1B, MEN4, P27KIP1, KIP1, cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Source: HGNC:1785
Biotype: protein coding gene
LEP
(Homo sapiens)Gene
Name: leptin
Synonyms: OBS, obesity factor, OB, leptin (obesity homolog, mouse), obese protein, obese, mouse, homolog of, FLJ94114, leptin (murine obesity homolog), LEPD
Source: HGNC:6553
Biotype: protein coding gene
ARID1A
(Homo sapiens)Gene
Name: AT-rich interaction domain 1A
Synonyms: chromatin remodeling factor p250, MRD14, hOSA1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, C1orf4, brain protein 120, SMARCF1, BM029, AT-rich interactive domain-containing protein 1A, SWI/SNF complex protein p270, osa homolog 1, OSA1, BAF250, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1, P270, OSA1 nuclear protein, BAF250a, hELD, BRG1-associated factor 250a, ARID domain-containing protein 1A, SWI-like protein, BRG1-associated factor 250, CSS2, AT rich interactive domain 1A (SWI-like), B120, ELD
Source: HGNC:11110
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
Ezh2
(Mus musculus)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: enhancer of zeste homolog (Drosophila), Enx-1, Enx1h, KMT6
Source: MGI:107940
Biotype: protein coding gene
EZH2
(Homo sapiens)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: ENX1, ENX-1, enhancer of zeste 2, lysine N-methyltransferase 6, KMT6, histone-lysine N-methyltransferase EZH2, enhancer of zeste homolog 2, WVS, EZH2b, WVS2, MGC9169, KMT6A, EZH1
Source: HGNC:3527
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, catenin (cadherin associated protein), beta 1, Bfc
Source: MGI:88276
Biotype: protein coding gene
Lep
(Mus musculus)Gene
Name: leptin
Synonyms: ob, OB, obese
Source: MGI:104663
Biotype: protein coding gene
Bax
(Mus musculus)Gene
Name: BCL2-associated X protein
Synonyms: Not Available
Source: MGI:99702
Biotype: protein coding gene
daf-18
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 18
Synonyms: T07A9.6, CELE_T07A9.6
Source: WB:WBGene00000913
Biotype: protein coding gene
H19
(Homo sapiens)Gene
Name: H19 imprinted maternally expressed transcript
Synonyms: D11S813E, WT2, PRO2605, MGC4485, H19, imprinted maternally expressed transcript (non-protein coding), ASM1, LINC00008, ASM, H19, imprinted maternally expressed transcript, MIR675HG, NCRNA00008, BWS
Source: HGNC:4713
Biotype: ncRNA gene
Il1b
(Mus musculus)Gene
Name: interleukin 1 beta
Synonyms: IL-1F2, IL-1B, IL-1beta, Il-1b
Source: MGI:96543
Biotype: protein coding gene
Antp
(Drosophila melanogaster)Gene
Name: Antennapedia
Synonyms: ANTC, antp, ANT-C, Nasobemia, Ant, Scx, Antp1, Antenapedia, DMANTPE1, Antp P1, Antp P2, DmAntp, Sex combs extra, CG1028, Aus, BG:DS07700.1, Ns, Sex comb extra, Hu, antennapedia, AntP1, Humeral, ANT-P, DRO15DC96Z, Antennapaedia, Antennapedia P2, AntP, Antennapedia P1, l(3)84Ba, ANTP, 3.4, Dm-Antennapedia, Atennapedia
Source: FB:FBgn0260642
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, dmp53, D-p53, Dmp53, Dm-P53, DmP53, dmP53, protein 53, CG31325, p53-like regulator of apoptosis and cell cycle, Drosophila p53
Source: FB:FBgn0039044
Biotype: protein coding gene
XPO1
(Homo sapiens)Gene
Name: exportin 1
Synonyms: Exportin-1 (required for chromosome region maintenance), chromosome region maintenance 1 protein homolog, CRM1, yeast, homolog, exportin 1 (CRM1 homolog, yeast), DKFZp686B1823, CRM-1, chromosome region maintenance 1 homolog, exportin 1 (CRM1, yeast, homolog), emb, exp1, CRM1, exportin-1
Source: HGNC:12825
Biotype: protein coding gene
Drice
(Drosophila melanogaster)Gene
Name: Death related ICE-like caspase
Synonyms: interleukin-1beta-converting enzyme, ice, ICE, Ice, drICE, caspase 3, drIce, drice, DriCE, DrICE, DrIce, Drice, CG7788, crice, DRICE, Drive, caspase-3
Source: FB:FBgn0019972
Biotype: protein coding gene
IL1B
(Homo sapiens)Gene
Name: interleukin 1 beta
Synonyms: preinterleukin 1 beta, IL1F2, interleukin-1 beta, catabolin, IL-1, IL1-BETA, IL1beta, IL-1 beta, interleukin 1beta, interleukin 1, beta, pro-interleukin-1-beta
Source: HGNC:5992
Biotype: protein coding gene
Sox14
(Drosophila melanogaster)Gene
Name: Sox box protein 14
Synonyms: Dsox-14, CG17263, SOXC, Sox-14, DSox14, DSox-14, sox14, SOX60B, SOX14, sox box protein 14, DSox60B, CG3090
Source: FB:FBgn0005612
Biotype: protein coding gene
hyx
(Drosophila melanogaster)Gene
Name: hyrax
Synonyms: Cdc73, Hyx, Hyrax, hyx/CDC73, CDC73, dCDC73, Parafibromin, CG11990
Source: FB:FBgn0037657
Biotype: protein coding gene
CTNNB1
(Homo sapiens)Gene
Name: catenin beta 1
Synonyms: beta-catenin, catenin (cadherin-associated protein), beta 1, MRD19, EVR7, catenin (cadherin-associated protein), beta 1, 88kDa, DKFZp686D02253, CTNNB, armadillo, FLJ37923, catenin beta-1, NEDSDV, FLJ25606
Source: HGNC:2514
Biotype: protein coding gene
tefu
(Drosophila melanogaster)Gene
Name: telomere fusion
Synonyms: atm/tefu, Tefu, ataxia telengiesctasia mutated, Drosophila ATM, ataxia telangiectasia mutated, CG6535, tef, A-T mutated, dATM, tefu/atm, ataxia-telangiectasia mutated, ATM, Ataxia Telangectasia Mutated, atm, Atm
Source: FB:FBgn0045035
Biotype: protein coding gene
Nfkb1
(Mus musculus)Gene
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: p50 subunit of NF kappaB, nuclear factor kappaB p50, NF-kB, NF kappaB1, NF-kappaB, p50/p105, p50, EBP-1, NFKB-p50, NF-kappaB p50
Source: MGI:97312
Biotype: protein coding gene
Fas
(Mus musculus)Gene
Name: Fas cell surface death receptor
Synonyms: Fas (TNF receptor superfamily member 6), AI196731, CD95, TNFR6, TNF receptor superfamily member 6, expressed sequence AI196731, lymphoproliferation, FasR, APO-1, Tnfrsf6, lpr
Source: MGI:95484
Biotype: protein coding gene
Pbrm1
(Mus musculus)Gene
Name: polybromo 1
Synonyms: expressed sequence AI507524, AI507524, BAF180, 2610016F04Rik, RIKEN cDNA 2610016F04 gene, 2310032M22Rik, RGD1565549, Pb1
Source: MGI:1923998
Biotype: protein coding gene
nAChRα7
(Drosophila melanogaster)Gene
Name: nicotinic Acetylcholine Receptor alpha7
Synonyms: CG8082, nAcRalpha-18C, nAcRalpha-7, gfA, nj522, nj520, Dalpha7, Dalpha7-nAChR, giant fibre A, Dalpha7 subunit of the nicotinic acetylcholine receptor, jumpless, nAChR, giant fiber A, Dalpha7 subunit of the acetylcholine receptor, Dalpha7 nAChR, non-jumper-522, non-jumper-520, Shaker cognate L, gfa, nachRalpha7, jpl, nAChR-Dalpha7, nAChR-gfa, nj54, non-jumper-507, nj75, nAChRalpha7, nAchRa7, AcR-Dalpha7, Dalpha7nAChRs, nAcRalpha18C, CG8109, CT24218, CG32538, non-jumper-75, nicotinic Acetylcholine Receptor alpha 18C, non-jumper-54, Da7, nj507
Source: FB:FBgn0086778
Biotype: protein coding gene
Vegfa
(Mus musculus)Gene
Name: vascular endothelial growth factor A
Synonyms: Vegf, vascular endothelial growth factor, VEGF188, VEGF111, VEGF-A, VPF, VEGF120, VEGF164
Source: MGI:103178
Biotype: protein coding gene
tcab-1
(Caenorhabditis elegans)Gene
Name: Telomerase CAjal Body protein 1 homolog 1
Synonyms: CELE_Y105E8A.8, Y105E8E.i, Y105E8E.g, Y105E8E.h, Y105E8A.8
Source: WB:WBGene00013669
Biotype: protein coding gene
GCN5
(Saccharomyces cerevisiae)Gene
Name: General Control Nonderepressible
Synonyms: YGR252W, SWI9, AAS104, KAT2, ADA4
Source: SGD:S000003484
Biotype: protein coding gene
Myc
(Mus musculus)Gene
Name: myelocytomatosis oncogene
Synonyms: Niard, c-myc, non-immunoglobulin rearranging DNA sequence, expressed sequence AU016757, RNCMYC, Nird, mMyc, bHLHe39, AU016757, Myc2
Source: MGI:97250
Biotype: protein coding gene
Stat92E
(Drosophila melanogaster)Gene
Name: Signal-transducer and activator of transcription protein at 92E
Synonyms: dSTAT92E/marelle, l(3)j6C8, D-stat, mrL, stat[92E], signal transducers and activator of transcription, STAT92, DmSTAT, signal transducer and activator of transcription, SD-stat, DRODSRC, Dstat92E, dstat, STAT92E, dSTAT, CG4257, Stat9E, stat92E, Stat, pSTAT, D-STAT, d-STAT, Stat92e, Dstat 92E, Stat1alpha-like, D-stat/stat92E, stat92, DSRC, stat, Signal-transducer and activator of transcription protein, Dst, Marelle, mrl, STAT 92E, Dstat, STAT92e, pSTAT92E, STAT, stat92e, D-Stat, dSTAT92E, Stat92E, mrl stat92E, marelle, DSTAT, l(3)06346, Sta92E, Stat92
Source: FB:FBgn0016917
Biotype: protein coding gene
hif-1
(Caenorhabditis elegans)Gene
Name: HIF (Hypoxia Inducible Factor) homologa 1
Synonyms: CELE_F38A6.3, F38A6.3
Source: WB:WBGene00001851
Biotype: protein coding gene
Cd44
(Mus musculus)Gene
Name: CD44 antigen
Synonyms: lymphocyte antigen 24, AW121933, METAA, AW146109, Ly-24, AU023126, HERMES, Pgp-1, RHAMM, CD44A, expressed sequence AW121933, expressed sequence AW146109, expressed sequence AU023126, phagocyte glycoprotein 1
Source: MGI:88338
Biotype: protein coding gene
CLN1
(Saccharomyces cerevisiae)Gene
Name: CycLiN
Synonyms: YMR199W
Source: SGD:S000004812
Biotype: protein coding gene
Ager
(Mus musculus)Gene
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Source: MGI:893592
Biotype: protein coding gene
Tnf
(Rattus norvegicus)Gene
Name: tumor necrosis factor
Synonyms: tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrosis factor (TNF superfamily, member 2), MGC124630, RATTNF, tumor necrosis factor-alpha, Tnfa, tumor necrosis factor-like, tumor necrosis factor alpha, tumor necrosis factor superfamily member 2, tumor necrosis factor superfamily, member 2, LOC103694380, cachectin
Source: RGD:3876
Biotype: protein coding gene
VEGFA
(Homo sapiens)Gene
Name: vascular endothelial growth factor A
Synonyms: MVCD1, VEGF, vascular endothelial growth factor, vascular endothelial growth factor A165, vascular endothelial growth factor A121, vascular endothelial growth factor A, long form, vascular permeability factor, MGC70609, VEGF-A, VPF, L-VEGF
Source: HGNC:12680
Biotype: protein coding gene
Myd88
(Mus musculus)Gene
Name: myeloid differentiation primary response gene 88
Synonyms: Not Available
Source: MGI:108005
Biotype: protein coding gene
STAT3
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 3
Synonyms: acute-phase response factor, ADMIO, signal transducer and activator of transcription 3 (acute-phase response factor), FLJ20882, MGC16063, ADMIO1, DNA-binding protein APRF, APRF, HIES
Source: HGNC:11364
Biotype: protein coding gene
SPOP
(Homo sapiens)Gene
Name: speckle type BTB/POZ protein
Synonyms: roadkill homolog 1, HIB homolog 1, NEDMACE, TEF2, NSDVS2, BTBD32, NEDMIDF, NSDVS1
Source: HGNC:11254
Biotype: protein coding gene