Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: 5'-flap endonuclease activity
RAD27
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: FEN1, ERC11, YKL113C, RTH1
Source: SGD:S000001596
Biotype: protein coding gene
DNA2
(Homo sapiens)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: RTS4, MGC133297, DNA replication helicase 2 homolog, PEOA6, DNA2 (DNA replication helicase, yeast, homolog)-like, DNA2 DNA replication helicase 2-like, KIAA0083, FLJ10063, DNA replication ATP-dependent helicase/nuclease DNA2, DNA2L, DNA2-like helicase, SCKL8, hDNA2, DNA replication ATP-dependent helicase-like homolog
Source: HGNC:2939
Biotype: protein coding gene
FEN1
(Homo sapiens)Gene
Name: flap structure-specific endonuclease 1
Synonyms: flap endonuclease 1, maturation factor 1, MF1, hFEN-1, FEN-1, maturation factor-1, RAD2, DNase IV
Source: HGNC:3650
Biotype: protein coding gene
DNA2
(Saccharomyces cerevisiae)Gene
Name: DNA synthesis defective
Synonyms: YHR164C, WEB2
Source: SGD:S000001207
Biotype: protein coding gene
EXO1
(Homo sapiens)Gene
Name: exonuclease 1
Synonyms: rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1, exonuclease I, HEX1, hExo1, hExoI
Source: HGNC:3511
Biotype: protein coding gene
mus201
(Drosophila melanogaster)Gene
Name: mutagen-sensitive 201
Synonyms: xpg/mus201, mus-201, 55A11T, ESTS:55A11T, XPG, mus(2)201, XPG[Dm], XPG[DM], rad202, DmXPG, CG32956, ERCC5, CG10890
Source: FB:FBgn0002887
Biotype: protein coding gene
FAN1
(Homo sapiens)Gene
Name: FANCD2 and FANCI associated nuclease 1
Synonyms: coiled-coil domain-containing protein MTMR15, myotubularin-related protein 15, FANCD2/FANCI-associated nuclease 1, fanconi-associated nuclease 1, KMIN, fanconi anemia associated nuclease 1, DKFZp451H236, KIAA1018, DKFZp686K16147, MTMR15, myotubularin related protein 15, RP11-540B6.6, hFAN1
Source: HGNC:29170
Biotype: protein coding gene
SLX1
(Saccharomyces cerevisiae)Gene
Name: Synthetic Lethal of unknown (X) function
Synonyms: YBR228W
Source: SGD:S000000432
Biotype: protein coding gene
Fan1
(Mus musculus)Gene
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: RIKEN cDNA 6030441H18 gene, RGD1566323, 6030441H18Rik, myotubularin related protein 15, Mtmr15
Source: MGI:3045266
Biotype: protein coding gene
GEN1
(Homo sapiens)Gene
Name: GEN1 Holliday junction 5' flap endonuclease
Synonyms: Gen homolog 1, endonuclease, Gen, DKFZp781F0986, GEN1, Holliday junction 5' flap endonuclease, flap endonuclease GEN homolog 1, FLJ36312, Holliday junction resolvase, Gen endonuclease homolog 1, FLJ40869
Source: HGNC:26881
Biotype: protein coding gene
SLX1A
(Homo sapiens)Gene
Name: SLX1 homolog A, structure-specific endonuclease subunit
Synonyms: GIY-YIG domain containing 1, structure-specific endonuclease subunit SLX1, SLX1B, SLX1 structure-specific endonuclease subunit homolog A, GIY-YIG domain-containing protein 1, GIYD2, GIYD1
Source: HGNC:20922
Biotype: protein coding gene
SLX1B
(Homo sapiens)Gene
Name: SLX1 homolog B, structure-specific endonuclease subunit
Synonyms: GIY-YIG domain containing 2, MGC2532, structure-specific endonuclease subunit SLX1, GIY-YIG domain-containing protein 1, MGC5178, SLX1 structure-specific endonuclease subunit homolog B, SLX1A, FLJ23439, GIYD2, GIYD1
Source: HGNC:28748
Biotype: protein coding gene
exo-1
(Caenorhabditis elegans)Gene
Name: EXOnuclease 1
Synonyms: F45G2.3, CELE_F45G2.3
Source: WB:WBGene00009731
Biotype: protein coding gene
Gen1
(Mus musculus)Gene
Name: GEN1, Holliday junction 5' flap endonuclease
Synonyms: RGD1559792, 5830483C08Rik, RIKEN cDNA 5830483C08 gene
Source: MGI:2443149
Biotype: protein coding gene
Exo1
(Mus musculus)Gene
Name: exonuclease 1
Synonyms: 5730442G03Rik, RIKEN cDNA 5730442G03 gene, Msa
Source: MGI:1349427
Biotype: protein coding gene
dna-2
(Caenorhabditis elegans)Gene
Name: yeast DNA helicase/endonuclease family 2
Synonyms: CELE_F43G6.1, F43G6.1
Source: WB:WBGene00001016
Biotype: protein coding gene
gen-1
(Caenorhabditis elegans)Gene
Name: GEN1 Holliday junction resolvase homolog 1
Synonyms: CELE_T12A2.8, T12A2.8
Source: WB:WBGene00020442
Biotype: protein coding gene
Fen1
(Mus musculus)Gene
Name: flap structure specific endonuclease 1
Synonyms: expressed sequence AW538437, AW538437, FEN-1
Source: MGI:102779
Biotype: protein coding gene
crn-1
(Caenorhabditis elegans)Gene
Name: Cell-death-Related Nuclease 1
Synonyms: Y47G6A.8, fen-1, CELE_Y47G6A.8
Source: WB:WBGene00000794
Biotype: protein coding gene
slx1
(Drosophila melanogaster)Gene
Name: nuclease slx1
Synonyms: SLX1, Slx1, CG18271, nuclease SLX1
Source: FB:FBgn0037263
Biotype: protein coding gene
EXO1
(Saccharomyces cerevisiae)Gene
Name: EXOnuclease
Synonyms: DHS1, YOR033C
Source: SGD:S000005559
Biotype: protein coding gene
Dna2
(Mus musculus)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: DNA2 DNA replication helicase 2-like (yeast), Dna2l, mKIAA0083, RIKEN cDNA E130315B21 gene, E130315B21Rik
Source: MGI:2443732
Biotype: protein coding gene
YEN1
(Saccharomyces cerevisiae)Gene
Name: Not Available
Synonyms: YER041W
Source: SGD:S000000843
Biotype: protein coding gene
SLX4
(Saccharomyces cerevisiae)Gene
Name: Synthetic Lethal of unknown (X) function
Synonyms: YLR135W
Source: SGD:S000004125
Biotype: protein coding gene
Fen1
(Rattus norvegicus)Gene
Name: flap structure-specific endonuclease 1
Synonyms: MGC94425, flap endonuclease 1, FEN-1, flap structure-specific endonuclease
Source: RGD:621821
Biotype: protein coding gene
Dna2
(Rattus norvegicus)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: DNA2 DNA replication helicase 2-like (yeast), Dna2l, DNA replication ATP-dependent helicase/nuclease DNA2, LOC309762, DNA2-like helicase, DNA replication helicase 2 homolog (yeast), DNA replication helicase 2 homolog, similar to DNA2 DNA replication helicase 2-like, DNA2 DNA replication helicase 2-like, DNA replication ATP-dependent helicase-like homolog
Source: RGD:1306791
Biotype: protein coding gene
Exo1
(Rattus norvegicus)Gene
Name: exonuclease 1
Synonyms: LOC305000
Source: RGD:1309465
Biotype: protein coding gene
fan-1
(Caenorhabditis elegans)Gene
Name: Fanconi Anemia-associated Nuclease 1
Synonyms: C01G5.8, CELE_C01G5.8
Source: WB:WBGene00015310
Biotype: protein coding gene
slx1b
(Danio rerio)Gene
Name: SLX1 homolog B, structure-specific endonuclease subunit
Synonyms: zmp:0000000823
Source: ZFIN:ZDB-GENE-130530-826
Biotype: protein coding gene
fen1
(Danio rerio)Gene
Name: flap structure-specific endonuclease 1
Synonyms: cb879
Source: ZFIN:ZDB-GENE-031112-11
Biotype: protein coding gene
Slc25a16
(Rattus norvegicus)Gene
Name: solute carrier family 25 member 16
Synonyms: graves disease carrier protein, solute carrier family 25, member 16, solute carrier family 25 (mitochondrial carrier), member 16, GDC, mitochondrial solute carrier protein homolog, solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16, LOC361836
Source: RGD:1311311
Biotype: protein coding gene
Slx1b
(Mus musculus)Gene
Name: SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Synonyms: AI853643, GIY-YIG domain containing 2, 2410170E21Rik, 1110030E23Rik, RIKEN cDNA 2410170E21 gene, 4833422P03Rik, RIKEN cDNA 4833422P03 gene, RGD1311568, expressed sequence AI853643, RIKEN cDNA 1110030E23 gene, Giyd1, Giyd2, LRRGT00058
Source: MGI:1915220
Biotype: protein coding gene
slx-1
(Caenorhabditis elegans)Gene
Name: yeast SLX (Synthetic Lethal X) homolog 1
Synonyms: F56A3.2, giyd-1, CELE_F56A3.2
Source: WB:WBGene00018909
Biotype: protein coding gene
Slx1b
(Rattus norvegicus)Gene
Name: SLX1 homolog B, structure-specific endonuclease subunit
Synonyms: MGC94602, GIY-YIG domain containing 2, structure-specific endonuclease subunit SLX1, LOC293489, RGD1311568, GIY-YIG domain-containing protein 1, SLX1 structure-specific endonuclease subunit homolog B, similar to RIKEN cDNA 4833422P03, Giyd1, Giyd2, LRRGT00058, SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Source: RGD:1311568
Biotype: protein coding gene
fan1
(Danio rerio)Gene
Name: FANCD2 and FANCI associated nuclease 1
Synonyms: si:ch211-201b11.2, wu:fi39f01, wu:fd06a07, si:ch211-163b1.2, fi39f01
Source: ZFIN:ZDB-GENE-030131-6225
Biotype: protein coding gene
exo1
(Danio rerio)Gene
Name: exonuclease 1
Synonyms: fc16e04, zgc:55521, wu:fc16e04
Source: ZFIN:ZDB-GENE-040426-2828
Biotype: protein coding gene
Dna2
(Drosophila melanogaster)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: DNA helicase, l(1)19-65, mus(1)107, mus(1)109, CG2990, mus107, mus109, DNA2, mutagen-sensitive 109, l(1)9Aa, DmDNA2, mus-109
Source: FB:FBgn0288690
Biotype: protein coding gene
Gen1
(Rattus norvegicus)Gene
Name: GEN1 Holliday junction 5' flap endonuclease
Synonyms: Gen homolog 1, endonuclease (Drosophila), Gen homolog 1, endonuclease, RGD1559792, flap endonuclease GEN homolog 1, Gen endonuclease homolog 1, Gen endonuclease homolog 1 (Drosophila), LOC298884, similar to RIKEN cDNA 5830483C08 gene
Source: RGD:1559792
Biotype: protein coding gene
Gen
(Drosophila melanogaster)Gene
Name: XPG-like endonuclease
Synonyms: GEN, DmGen, DmGEN, BcDNA:GM10765, mutagen-sensitive 324, mus324, CG10670
Source: FB:FBgn0263831
Biotype: protein coding gene
DIN7
(Saccharomyces cerevisiae)Gene
Name: DNA Damage INducible
Synonyms: YDR263C, DIN3
Source: SGD:S000002671
Biotype: protein coding gene
dna2
(Danio rerio)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: si:ch211-1n9.7
Source: ZFIN:ZDB-GENE-090313-71
Biotype: protein coding gene
Fan1
(Rattus norvegicus)Gene
Name: FANCD2 and FANCI associated nuclease 1
Synonyms: coiled-coil domain-containing protein MTMR15, fanconi-associated nuclease 1, FANCD2/FANCI-associated nuclease 1, LOC309256, RGD1566323, myotubularin related protein 15, Mtmr15, similar to mKIAA1018 protein
Source: RGD:1566323
Biotype: protein coding gene
zgc:110269
(Danio rerio)Gene
Name: zgc:110269
Synonyms: im:7147072
Source: ZFIN:ZDB-GENE-050417-81
Biotype: protein coding gene
tos
(Drosophila melanogaster)Gene
Name: tosca
Synonyms: Tosca, DmTosca, CG10387
Source: FB:FBgn0015553
Biotype: protein coding gene
Fen1
(Drosophila melanogaster)Gene
Name: Flap endonuclease 1
Synonyms: EG:EG0003.3, CG8648, FEN1, flap endonuclease-1, DmFEN-1, fen1
Source: FB:FBgn0025832
Biotype: protein coding gene