Version: 8.1.0Date: Fri Apr 18 2025
Gene Molecular Function: GTPase activator activity
GTS1
(Saccharomyces cerevisiae)Gene
Name: Glycine Threonine Serine repeat protein
Synonyms: YGL181W, LSR1, FHT1
Source: SGD:S000003149
Biotype: protein coding gene
SYNGAP1
(Homo sapiens)Gene
Name: synaptic Ras GTPase activating protein 1
Synonyms: SYNGAP, Ras/Rap GTPase-activating protein 1, synaptic Ras GTPase activating protein, 135kDa, MRD5, RASA1, ras/Rap GTPase-activating protein SynGAP, RASA5, ras GTPase-activating protein SynGAP, synaptic Ras GTPase-activating protein 1, synaptic Ras GTPase activating protein 1 homolog, KIAA1938, DKFZp761G1421, neuronal RasGAP
Source: HGNC:11497
Biotype: protein coding gene
C9orf72
(Homo sapiens)Gene
Name: C9orf72-SMCR8 complex subunit
Synonyms: FTDALS, chromosome 9 open reading frame 72, DENNL72, MGC23980, FTDALS1, hypothetical protein LOC203228, uncharacterized protein C9orf72, DENND9, guanine nucleotide exchange C9orf72, RP11-27J8.2, ALSFTD, guanine nucleotide exchange factor C9orf72
Source: HGNC:28337
Biotype: protein coding gene
NF1
(Homo sapiens)Gene
Name: neurofibromin 1
Synonyms: truncated neurofibromin 1, neurofibromin, WSS, DKFZp686J1293, FLJ21220, neurofibromatosis-related protein NF-1, neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease), NFNS, VRNF, neurofibromatosis 1
Source: HGNC:7765
Biotype: protein coding gene
Nrp1
(Mus musculus)Gene
Name: neuropilin 1
Synonyms: Npn1, Neuropilin-1, NPN-1, NP-1, Nrp
Source: MGI:106206
Biotype: protein coding gene
pxf-1
(Caenorhabditis elegans)Gene
Name: PDZ eXchange Factor 1
Synonyms: CELE_T14G10.2, yk17d8.3, T14G10.2, ra-gef
Source: WB:WBGene00004254
Biotype: protein coding gene
JUN
(Homo sapiens)Gene
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Synonyms: v-jun sarcoma virus 17 oncogene homolog, jun oncogene, AP1, enhancer-binding protein AP1, proto-oncogene c-Jun, AP-1, transcription factor AP-1, cJUN, transcription factor AP-1 subunit Jun, c-Jun, Jun activation domain binding protein, transcription factor Jun, activator protein 1, v-jun avian sarcoma virus 17 oncogene homolog, p39, jun proto-oncogene, proto-oncogene cJun
Source: HGNC:6204
Biotype: protein coding gene
DOCK7
(Homo sapiens)Gene
Name: dedicator of cytokinesis 7
Synonyms: dedicator of cytokinesis protein 7, ZIR2, EIEE23, KIAA1771, DEE23
Source: HGNC:19190
Biotype: protein coding gene
SRGAP2
(Homo sapiens)Gene
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FNBP2, formin-binding protein 2, KIAA0456, SLIT-ROBO GAP2, srGAP3, formin binding protein 2, rho GTPase-activating protein 34, SLIT-ROBO Rho GTPase-activating protein 2, RP11-312O7.2, SRGAP2A, ARHGAP34
Source: HGNC:19751
Biotype: protein coding gene
LRRK2
(Homo sapiens)Gene
Name: leucine rich repeat kinase 2
Synonyms: leucine-rich repeat serine/threonine-protein kinase 2, RIPK7, leucine-rich repeat kinase 2, ROCO2, augmented in rheumatoid arthritis 17, AURA17, PARK8, DARDARIN, Parkinson disease (autosomal dominant) 8
Source: HGNC:18618
Biotype: protein coding gene
Bcr
(Mus musculus)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, RIKEN cDNA 5133400C09 gene, AI853148, expressed sequence AI853148, mKIAA3017, expressed sequence AI561783, AI561783, breakpoint cluster region
Source: MGI:88141
Biotype: protein coding gene
Lrrk2
(Mus musculus)Gene
Name: leucine-rich repeat kinase 2
Synonyms: cDNA sequence, clone 3-75, Gm927, RIKEN cDNA 4921513O20 gene, AW561911, RIKEN cDNA D630001M17 gene, RIKEN cDNA 9330188B09 gene, 4921513O20Rik, D630001M17Rik, LOC381026, gene model 927, (NCBI), cI-46, 9330188B09Rik
Source: MGI:1913975
Biotype: protein coding gene
FLCN
(Homo sapiens)Gene
Name: folliculin
Synonyms: BHD skin lesion fibrofolliculoma protein, birt-Hogg-Dube syndrome protein, FLJ45004, DENND8B, MGC23445, DKFZp547A118, MGC17998, FLCL, BHD, FLJ99377
Source: HGNC:27310
Biotype: protein coding gene
Ranbp2
(Mus musculus)Gene
Name: RAN binding protein 2
Synonyms: expressed sequence AI256741, AI256741, RGD1560047, A430087B05Rik, RIKEN cDNA A430087B05 gene
Source: MGI:894323
Biotype: protein coding gene
BCR
(Homo sapiens)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: ALL, D22S662, CML, PHL, renal carcinoma antigen NY-REN-26, FLJ16453, FGFR1/BCR chimera protein, BCR/FGFR1 chimera protein, D22S11, breakpoint cluster region, BCR1
Source: HGNC:1014
Biotype: protein coding gene
gap-2
(Caenorhabditis elegans)Gene
Name: GTPase Activating Protein family 2
Synonyms: CELE_ZK899.8, ZK899.8
Source: WB:WBGene00001516
Biotype: protein coding gene
DNM1L
(Homo sapiens)Gene
Name: dynamin 1 like
Synonyms: Dnm1p/Vps1p-like protein, DYMPLE, EMPF1, DYNIV-11, dynamin-related protein 1, dynamin-1-like protein, DLP1, dynamin family member proline-rich carboxyl-terminal domain less, dynamin-like protein 4, DRP1, OPA5, dynamin-like protein IV, VPS1, DVLP, HDYNIV, EMPF, dynamin 1-like, FLJ41912
Source: HGNC:2973
Biotype: protein coding gene
Tsc2
(Mus musculus)Gene
Name: TSC complex subunit 2
Synonyms: Rc, Nafld, tuberous sclerosis 2, tuberin
Source: MGI:102548
Biotype: protein coding gene
Plcb1
(Mus musculus)Gene
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik, RATPHOSPHB, AI132408, RIKEN cDNA 3110043I21 gene, Phosphb, expressed sequence AI132408, PLCbeta1, PLC'1, mKIAA0581
Source: MGI:97613
Biotype: protein coding gene
Chm
(Mus musculus)Gene
Name: CHM Rab escort protein
Synonyms: Rep-1
Source: MGI:892979
Biotype: protein coding gene
Rgs7
(Mus musculus)Gene
Name: regulator of G protein signaling 7
Synonyms: Not Available
Source: MGI:1346089
Biotype: protein coding gene
Gipc1
(Mus musculus)Gene
Name: GIPC PDZ domain containing family, member 1
Synonyms: TIP-2, neurophilin1-IP, Rgs19, Gipc, TaxIP2, Semcap1, Glut1CIP, Rgs19ip1, semaF cytoplasmic domain associated protein 1, regulator of G-protein signaling 19 interacting protein 1, synectin
Source: MGI:1926252
Biotype: protein coding gene
Rgs5
(Mus musculus)Gene
Name: regulator of G-protein signaling 5
Synonyms: 1110070A02Rik, RIKEN cDNA 1110070A02 gene
Source: MGI:1098434
Biotype: protein coding gene
Rangap1
(Mus musculus)Gene
Name: RAN GTPase activating protein 1
Synonyms: failure to undergo gastrulation, C79654, Fug1, expressed sequence C79654
Source: MGI:103071
Biotype: protein coding gene
Stxbp5l
(Mus musculus)Gene
Name: syntaxin binding protein 5-like
Synonyms: RIKEN cDNA A830015P08 gene, tomosyn-2, type 2 diabetes mellitus 1, t2md1, insulin level locus 1, LLGL4, A830015P08Rik, T2dm1
Source: MGI:2443815
Biotype: protein coding gene
Stxbp5
(Mus musculus)Gene
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: LGL3, expressed sequence AW742610, RIKEN cDNA 4930565N16 gene, 0710001E20Rik, mKIAA1006, 4930565N16Rik, RIKEN cDNA 0710001E20 gene, tomosyn 1, AW742610
Source: MGI:1926058
Biotype: protein coding gene
Jun
(Mus musculus)Gene
Name: jun proto-oncogene
Synonyms: c-jun, Junc, Jun-C oncogene
Source: MGI:96646
Biotype: protein coding gene
Thy1
(Mus musculus)Gene
Name: thymus cell antigen 1, theta
Synonyms: Thy 1.2, T25, CD90, Thy1.1, CD7, Thy1.2, Thy-1, Thy-1.2, theta
Source: MGI:98747
Biotype: protein coding gene
Arrb1
(Mus musculus)Gene
Name: arrestin, beta 1
Synonyms: AW208571, expressed sequence AW208571, 1200006I17Rik, RIKEN cDNA 1200006I17 gene, RIKEN cDNA G430100A01 gene, BARRES, G430100A01Rik, beta-arrestin1
Source: MGI:99473
Biotype: protein coding gene
RASA1
(Homo sapiens)Gene
Name: RAS p21 protein activator 1
Synonyms: p120, CM-AVM, PKWS, CMAVM1, GTPase-activating protein, RAS p21 protein activator (GTPase activating protein) 1, GAP, DKFZp434N071, p120GAP, p120RASGAP, ras GTPase-activating protein 1, RASGAP, CMAVM, RASA, triphosphatase-activating protein
Source: HGNC:9871
Biotype: protein coding gene
Rbpn-5
(Drosophila melanogaster)Gene
Name: Rabaptin-5
Synonyms: CG4030, Rabaptin5
Source: FB:FBgn0034585
Biotype: protein coding gene
rga-9
(Caenorhabditis elegans)Gene
Name: Rho GTPase Activating protein 9
Synonyms: 2RSSE.1, CELE_2RSSE.1
Source: WB:WBGene00007064
Biotype: protein coding gene
RhoGAP1A
(Drosophila melanogaster)Gene
Name: Rho GTPase activating protein at 1A
Synonyms: BCR, rhoGAP1A, CG40494, RhoGAP1A, RhoGAP, CG17617, EG:23E12.5, CG17960, EG:23E12.2, CG40453
Source: FB:FBgn0025836
Biotype: protein coding gene
gap-1
(Caenorhabditis elegans)Gene
Name: GTPase Activating Protein family 1
Synonyms: suv-1, CELE_T24C12.2, sli-5, T24C12.2
Source: WB:WBGene00001515
Biotype: protein coding gene
BEM2
(Saccharomyces cerevisiae)Gene
Name: Bud EMergence
Synonyms: TSL1, YER155C, SUP9, IPL2
Source: SGD:S000000957
Biotype: protein coding gene
LST4
(Saccharomyces cerevisiae)Gene
Name: Lethal with Sec Thirteen
Synonyms: YKL176C
Source: SGD:S000001659
Biotype: protein coding gene
SEC12
(Saccharomyces cerevisiae)Gene
Name: SECretory
Synonyms: YNR026C, SED2
Source: SGD:S000005309
Biotype: protein coding gene
Tbcd
(Mus musculus)Gene
Name: tubulin-specific chaperone d
Synonyms: RIKEN cDNA 2310057L06 gene, mKIAA0988, A030005L14Rik, 2310057L06Rik, RIKEN cDNA A030005L14 gene
Source: MGI:1919686
Biotype: protein coding gene
Syngap1
(Mus musculus)Gene
Name: synaptic Ras GTPase activating protein 1 homolog (rat)
Synonyms: Syngap, Gm1963, gene model 1963, (NCBI)
Source: MGI:3039785
Biotype: protein coding gene
Tbc1d4
(Mus musculus)Gene
Name: TBC1 domain family, member 4
Synonyms: RGD1561609, AS160, expressed sequence AV295684, 5930406J04Rik, RIKEN cDNA 5930406J04 gene, AV295684
Source: MGI:2429660
Biotype: protein coding gene
PDGFRB
(Homo sapiens)Gene
Name: platelet derived growth factor receptor beta
Synonyms: PDGFR-beta, OPDKD, CD140 antigen-like family member B, beta-type platelet-derived growth factor receptor, PDGFR-1, platelet-derived growth factor receptor beta, IMF1, NDEL1-PDGFRB, PDGF-R-beta, PDGFR1, KOGS, Activated tyrosine kinase PDGFRB, platelet-derived growth factor receptor, beta polypeptide, JTK12, PDGFR, IBGC4, platelet-derived growth factor receptor 1, PENTT, CD140B
Source: HGNC:8804
Biotype: protein coding gene
BEM3
(Saccharomyces cerevisiae)Gene
Name: Bud EMergence
Synonyms: YPL115C
Source: SGD:S000006036
Biotype: protein coding gene
RAPGEF2
(Homo sapiens)Gene
Name: Rap guanine nucleotide exchange factor 2
Synonyms: RA(Ras/Rap1A-associating)-GEF, Rap-GEP, PDZ-GEF1, nRap GEP, RA-GEF-1, CNrasGEF, Rap guanine nucleotide exchange factor (GEF) 2, NRAPGEP, cyclic nucleotide ras GEF, PDZ domain containing guanine nucleotide exchange factor (GEF) 1, PDZ domain-containing guanine nucleotide exchange factor 1, neural RAP guanine nucleotide exchange protein, RAGEF, RA-GEF, PDZGEF1, ras/Rap1-associating GEF-1
Source: HGNC:16854
Biotype: protein coding gene
SMAP1
(Homo sapiens)Gene
Name: small ArfGAP 1
Synonyms: stromal membrane-associated GTPase-activating protein 1, SMAP-1, FLJ13159, FLJ42245, stromal membrane-associated protein 1
Source: HGNC:19651
Biotype: protein coding gene
NOD2
(Homo sapiens)Gene
Name: nucleotide binding oligomerization domain containing 2
Synonyms: BLAU, CD, caspase recruitment domain protein 15, NOD2B, caspase recruitment domain family, member 15, IBD1, YAOS, NOD-like receptor C2, ACUG, PSORAS1, nucleotide-binding oligomerization domain-containing protein 2, NLRC2, NLR family, CARD domain containing 2, BLAUS, nucleotide-binding oligomerization domain containing 2, caspase recruitment domain-containing protein 15, inflammatory bowel disease protein 1, Inflammatory bowel disease-1 (Crohn disease), CARD15, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2, CLR16.3
Source: HGNC:5331
Biotype: protein coding gene
MYO5A
(Homo sapiens)Gene
Name: myosin VA
Synonyms: MYR12, dilute myosin heavy chain, non-muscle, GS1, myosin-12, MYO5, myoxin, myosin VA (heavy chain 12, myoxin), myosin V, unconventional myosin-Va, myosin, heavy polypeptide kinase, MYH12, myosin-Va
Source: HGNC:7602
Biotype: protein coding gene
Tbc1d24
(Mus musculus)Gene
Name: TBC1 domain family, member 24
Synonyms: RIKEN cDNA C530046L02 gene, C530046L02Rik, mKIAA1171, RGD1306143
Source: MGI:2443456
Biotype: protein coding gene
npp-9
(Caenorhabditis elegans)Gene
Name: Nuclear Pore complex Protein 9
Synonyms: CELE_F59A2.1, Nup358, F59A2.1
Source: WB:WBGene00003795
Biotype: protein coding gene
ARHGAP18
(Homo sapiens)Gene
Name: Rho GTPase activating protein 18
Synonyms: rho-type GTPase-activating protein 18, bA307O14.2, MGC138145, MGC126757, SENEX, FLJ25728, rho GTPase-activating protein 18, MacGAP
Source: HGNC:21035
Biotype: protein coding gene
Ophn1
(Mus musculus)Gene
Name: oligophrenin 1
Synonyms: wavy tiger, Wtgr, Opn1, C130037N19Rik, RIKEN cDNA C130037N19 gene
Source: MGI:2151070
Biotype: protein coding gene