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bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding

Branch: molecular function

Genes: E2F5 (Hsa)...E2f4 (Rno)...E2f5 (Mmu)...E2f1 (Mmu)...E2f4 (Mmu)

Genes Annotated with this GO Term (1888)

DNA-binding transcription repressor activity

Gene Ontology

Source: GO:0001217

Synonyms:

bacterial-type DNA binding transcription repressor activity
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

Branch: molecular function

Genes: E2f8 (Mmu)...E2f7 (Rno)...E2F8 (Hsa)...e2f7 (Dre)...E2f8 (Rno)

Genes Annotated with this GO Term (1046)

hepatocyte differentiation

Gene Ontology

Source: GO:0070365

Synonyms:

liver cell differentiation

Branch: biological process

Genes: E2f8 (Mmu)...E2f7 (Rno)...E2F8 (Hsa)...e2f7 (Dre)...E2f8 (Rno)

Genes Annotated with this GO Term (58)

trophoblast giant cell differentiation

Gene Ontology

Source: GO:0060707

Synonyms: Not Available

Branch: biological process

Genes: E2f8 (Mmu)...E2f7 (Rno)...E2F8 (Hsa)...E2f8 (Rno)...E2f7 (Mmu)

Genes Annotated with this GO Term (53)

EP2 subtype prostaglandin E2 receptor binding

Gene Ontology

Source: GO:0031865

Synonyms:

EP2 subtype prostaglandin E2 receptor ligand
prostanoid EP2 receptor binding

Branch: molecular function

Symbol: EP2 subtype prostaglandin E2 receptor binding

Synonyms: EP2 subtype prostaglandin E2 receptor ligand

Name: EP2 subtype prostaglandin E2 receptor binding

Definition: Binding to an EP2 subtype prostaglandin E2 receptor....Binding to an EP2 subtype prostaglandin E2 receptor.

EP4 subtype prostaglandin E2 receptor binding

Gene Ontology

Source: GO:0031867

Synonyms:

EP4 subtype prostaglandin E2 receptor ligand
prostanoid EP4 receptor binding

Branch: molecular function

Symbol: EP4 subtype prostaglandin E2 receptor binding

Synonyms: EP4 subtype prostaglandin E2 receptor ligand

Name: EP4 subtype prostaglandin E2 receptor binding

Definition: Binding to an EP4 subtype prostaglandin E2 receptor....Binding to an EP4 subtype prostaglandin E2 receptor.

Genes Annotated with this GO Term (4)

EP3 subtype prostaglandin E2 receptor binding

Gene Ontology

Source: GO:0031866

Synonyms:

EP3 subtype prostaglandin E2 receptor ligand
prostanoid EP3 receptor binding

Branch: molecular function

Symbol: EP3 subtype prostaglandin E2 receptor binding

Synonyms: EP3 subtype prostaglandin E2 receptor ligand

Name: EP3 subtype prostaglandin E2 receptor binding

Definition: Binding to an EP3 subtype prostaglandin E2 receptor....Binding to an EP3 subtype prostaglandin E2 receptor.

multi-ciliated epithelial cell differentiation

Gene Ontology

Source: GO:1903251

Synonyms:

multiciliate cell differentiation

Branch: biological process

Genes: E2F4 (Hsa)...E2f4 (Mmu)...e2f5 (Dre)

Genes Annotated with this GO Term (34)

EP1 subtype prostaglandin E2 receptor binding

Gene Ontology

Source: GO:0031864

Synonyms:

EP1 subtype prostaglandin E2 receptor ligand
prostanoid EP1 receptor binding

Branch: molecular function

Symbol: EP1 subtype prostaglandin E2 receptor binding

Synonyms: EP1 subtype prostaglandin E2 receptor ligand

Name: EP1 subtype prostaglandin E2 receptor binding

Definition: Binding to an EP1 subtype prostaglandin E2 receptor....Binding to an EP1 subtype prostaglandin E2 receptor.

RNA polymerase II transcription regulator complex

Gene Ontology

Source: GO:0090575

Synonyms:

RNA polymerase II transcription factor complex

Branch: cellular component

Genes: E2f7 (Mmu)...E2f5 (Rno)...E2F4 (Hsa)...E2F6 (Hsa)...e2f7 (Dre)

Genes Annotated with this GO Term (1167)

Atg8-family conjugating enzyme activity

Gene Ontology

Source: GO:0141046

Synonyms:

APG8 conjugating enzyme activity
Atg8 conjugating enzyme activity

Branch: molecular function

Synonyms: E2...E2

Genes Annotated with this GO Term (7)

15-oxoprostaglandin 13-oxidase [NAD(P)+] activity

Gene Ontology

Source: GO:0047522

Synonyms:

(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity
15-oxo-Delta(13)-prostaglandin reductase activity

Branch: molecular function

Definition: Catalysis of the reaction: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(P)+ = 15-oxoprostaglandin E2 +...Catalysis of the reaction: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(P)+ = 15-oxoprostaglandin E2 +

Genes Annotated with this GO Term (13)

DNA endoreduplication

Gene Ontology

Source: GO:0042023

Synonyms:

DNA endoreplication
DNA re-duplication

Branch: biological process

Genes: E2f2 (Dme)...E2f1 (Dme)

Genes Annotated with this GO Term (22)

cyclin E2-CDK2 complex

Gene Ontology

Source: GO:0097135

Synonyms: Not Available

Branch: cellular component

Definition: A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2)....A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2).

Symbol: cyclin E2-CDK2 complex

Genes Annotated with this GO Term (7)

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

Gene Ontology

Source: GO:0006977

Synonyms:

positive regulation of cell cycle arrest by p53-mediated DNA damage response

Branch: biological process

Genes: E2f7 (Rno)...E2f7 (Mmu)...E2F7 (Hsa)

Genes Annotated with this GO Term (51)

centriole assembly

Gene Ontology

Source: GO:0098534

Synonyms: Not Available

Branch: biological process

Genes: E2F4 (Hsa)...E2f4 (Mmu)

Genes Annotated with this GO Term (147)

cis-regulatory region sequence-specific DNA binding

Gene Ontology

Source: GO:0000987

Synonyms:

bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
bacterial-type RNA polymerase enhancer sequence-specific DNA binding

Branch: molecular function

Genes: E2f1 (Mmu)...E2f7 (Mmu)...E2f8 (Mmu)...E2f2 (Rno)...E2f3 (Rno)

Genes Annotated with this GO Term (5311)

anoikis

Gene Ontology

Source: GO:0043276

Synonyms:

detachment induced cell death
suspension induced apoptosis

Branch: biological process

Genes: E2f1 (Mmu)...E2F1 (Hsa)...E2f1 (Rno)

Genes Annotated with this GO Term (31)

prostaglandin E2 9-reductase activity

Gene Ontology

Source: GO:0050221

Synonyms:

(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity
9-keto-prostaglandin E2 reductase activity

Branch: molecular function

Symbol: prostaglandin E2 9-reductase activity

Synonyms: 9-keto-prostaglandin E2 reductase activity

Name: prostaglandin E2 9-reductase activity

Genes Annotated with this GO Term (3)

epithelial cell development

Gene Ontology

Source: GO:0002064

Synonyms: Not Available

Branch: biological process

Genes: E2f4 (Rno)...E2f4 (Mmu)...E2F4 (Hsa)

Genes Annotated with this GO Term (1137)

positive regulation of vascular associated smooth muscle cell apoptotic process

Gene Ontology

Source: GO:1905461

Synonyms:

activation of VSMC apoptosis
activation of VSMC apoptotic process

Branch: biological process

Genes: E2f3 (Mmu)...E2F3 (Hsa)...E2f3 (Rno)

Genes Annotated with this GO Term (40)

intrinsic apoptotic signaling pathway by p53 class mediator

Gene Ontology

Source: GO:0072332

Synonyms:

intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
signal transduction by p53 class mediator resulting in induction of apoptosis

Branch: biological process

Genes: E2f1 (Mmu)...E2F2 (Hsa)...E2f1 (Rno)...E2f2 (Rno)...E2F1 (Hsa)