Version: 8.0.0
Date: Tue Jan 28 2025
7,852 results for cblb

negative regulation of T cell receptor signaling pathway

Gene Ontology
Source: GO:0050860
Synonyms:
  • down regulation of T cell receptor signaling pathway
  • down-regulation of T cell receptor signaling pathway
Branch: biological process
Genes: Cblb (Mmu)...CBLB (Hsa)...Cblb (Rno)

negative regulation of epidermal growth factor receptor signaling pathway

Gene Ontology
Source: GO:0042059
Synonyms:
  • down regulation of epidermal growth factor receptor signaling pathway
  • down-regulation of epidermal growth factor receptor signaling pathway
Branch: biological process
Genes: Cblb (Mmu)...cblb (Dre)...CBLB (Hsa)...Cblb (Rno)

TM.KDP-Cblb/Nyo

(Rattus norvegicus)
Model
Id: RGD:2304297
Synonyms: TM.KDP-Cblb/Nyo; TM.KDP-Cblb congenic; NBRP Rat No: 0354, TM.KDP-Cblb/Nyo
Name: TM.KDP-<Cblb>/Nyo

PVG.KDP-Cblb/Nyo

(Rattus norvegicus)
Model
Id: RGD:8549778
Synonyms: NBRP Rat No: 0630, PVG.KDP-Cblb/Nyo, PVG.KDP-Cblb congenic, PK congenic
Name: PVG.KDP-<Cblb

KDP-Tg(INS-Cblb)1Nyo

(Rattus norvegicus)
Model
Id: RGD:2304065
Synonyms: NBRP Rat No: 0199
Name: KDP-Tg(INS-Cblb)1Nyo

regulation of T cell receptor signaling pathway

Gene Ontology
Source: GO:0050856
Synonyms:
  • regulation of T lymphocyte receptor signaling pathway
  • regulation of T lymphocyte receptor signalling pathway
Branch: biological process
Genes: Cblb (Mmu)

regulation of cell adhesion

Gene Ontology
Source: GO:0030155
Synonyms:
  • cell adhesion receptor regulator activity
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

phosphotyrosine residue binding

Gene Ontology
Source: GO:0001784
Synonyms:
  • phosphotyrosine binding
Branch: molecular function
Genes: Cblb (Mmu)...cblb (Dre)...CBLB (Hsa)...Cblb (Rno)

stomach carcinoma

Disease
Source: DOID:5517
Definition: A stomach cancer that is located_in the stomach.
Genes: cblb.L (Xla)...CBLB (Hsa)...cblb (Xtr)...Cblb (Rno)...Cblb (Mmu)

response to gravity

Gene Ontology
Source: GO:0009629
Synonyms:
  • response to gravitational stimulus
Branch: biological process
Genes: Cblb (Rno)

regulation of protein binding

Gene Ontology
Source: GO:0043393
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)

KDP-Tg(CAG-Cblb)1Nyo

(Rattus norvegicus)
Model
Id: RGD:2304066
Synonyms: NBRP Rat No: 0198
Name: KDP-Tg(CAG-Cblb)1Nyo

KDP-Tg(H2Kd-Cblb)2Nyo

(Rattus norvegicus)
Model
Id: RGD:2304063
Synonyms: NBRP Rat No: 0197
Name: KDP-Tg(H2Kd-Cblb)2Nyo

T cell activation

Gene Ontology
Source: GO:0042110
Synonyms:
  • T lymphocyte activation
  • T-cell activation
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

Hsap\CBLBUAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0320818
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\CBLB
Construct Expressed Component: CBLB (Hsa)

lung squamous cell carcinoma

Disease
Source: DOID:3907
Definition: A non-small cell lung carcinoma that has_material_basis_in the squamous cell.
Genes: cblb.L (Xla)...CBLB (Hsa)...cblb (Dre)...cblb (Xtr)...Cblb (Rno)

receptor tyrosine kinase binding

Gene Ontology
Source: GO:0030971
Synonyms:
  • transmembrane receptor protein tyrosine kinase ligand binding
Branch: molecular function
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)...cblb (Dre)

TM.KDP-Cblb(D9Rat13-D9Rat4)(D12Rat5-D12Rat45)(D18Mit9-D18Rat44)/Nyo

(Rattus norvegicus)
Model
Id: RGD:11041128
Synonyms: NBRP Rat No: 0807, TM.KDP-Cblb(D9Rat13-D9Rat4)(D12Rat5-D12Rat45)(D18Mit9-D18Rat44)/Nyo, TM.KDP-Chr9,12,18 triple congenic
Name: TM.KDP-<Cblb>()()()/Nyo

regulation of GTPase activity

Gene Ontology
Source: GO:0043087
Synonyms:
  • regulation of ARF GTPase activity
  • regulation of Cdc42 GTPase activity
Branch: biological process
Genes: Cblb (Mmu)

positive regulation of protein catabolic process

Gene Ontology
Source: GO:0045732
Synonyms:
  • activation of cellular protein breakdown
  • activation of cellular protein catabolic process
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

positive regulation of protein ubiquitination

Gene Ontology
Source: GO:0031398
Synonyms:
  • activation of protein ubiquitination
  • stimulation of protein ubiquitination
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

T cell receptor signaling pathway

Gene Ontology
Source: GO:0050852
Synonyms:
  • T lymphocyte receptor signaling pathway
  • T lymphocyte receptor signalling pathway
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

NLS-bearing protein import into nucleus

Gene Ontology
Source: GO:0006607
Synonyms:
  • NLS-bearing substrate import into cell nucleus
  • NLS-bearing substrate import into nucleus
Branch: biological process
Genes: CBLB (Hsa)

protein catabolic process

Gene Ontology
Source: GO:0030163
Synonyms:
  • cellular protein breakdown
  • cellular protein catabolic process
Branch: biological process
Genes: CBLB (Hsa)...Cblb (Rno)...Cblb (Mmu)

response to hormone

Gene Ontology
Source: GO:0009725
Synonyms:
  • growth regulator
  • response to hormone stimulus
Branch: biological process
Genes: Cblb (Rno)

membrane raft

Gene Ontology
Source: GO:0045121
Synonyms:
  • GEM domain
  • glycolipid-enriched membrane domain
Branch: cellular component
Genes: Cblb (Rno)...Cblb (Mmu)...CBLB (Hsa)...cblb (Dre)

type 1 diabetes mellitus

Disease
Source: DOID:9744
Definition: A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Genes: cblb.L (Xla)...cblb (Xtr)...Cblb (Rno)...Cblb (Mmu)...CBLB (Hsa)

ubiquitin-protein transferase activity

Gene Ontology
Source: GO:0004842
Synonyms:
  • E2
  • E3
Branch: molecular function
Genes: Cblb (Rno)...Cblb (Mmu)...CBLB (Hsa)...cblb (Dre)

cellular response to hydrogen peroxide

Gene Ontology
Source: GO:0070301
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Rno)

cell surface receptor signaling pathway

Gene Ontology
Source: GO:0007166
Synonyms:
  • cell surface receptor linked signal transduction
  • cell surface receptor linked signaling pathway
Branch: biological process
Genes: Cblb (Rno)...CBLB (Hsa)...cblb (Dre)

lung non-small cell carcinoma

Disease
Source: DOID:3908
Definition: A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
Genes: cblb.L (Xla)...Cblb (Mmu)...CBLB (Hsa)...cblb (Xtr)...Cblb (Rno)

postsynapse

Gene Ontology
Source: GO:0098794
Synonyms: Not Available
Branch: cellular component
Genes: Cblb (Rno)...Cblb (Mmu)...CBLB (Hsa)

ubiquitin protein ligase activity

Gene Ontology
Source: GO:0061630
Synonyms:
  • E3
  • ER-associated E3 ligase
Branch: molecular function
Genes: Cblb (Mmu)...CBLB (Hsa)...Cblb (Rno)...cblb (Dre)

protein ubiquitination

Gene Ontology
Source: GO:0016567
Synonyms:
  • protein ubiquitinylation
  • protein ubiquitylation
Branch: biological process
Genes: Cblb (Mmu)...CBLB (Hsa)...Cblb (Rno)...cblb (Dre)

immune response

Gene Ontology
Source: GO:0006955
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)...CBLB (Hsa)...Cblb (Rno)

(GRCh38)12:109557129C>T

(Homo sapiens)
Allele/Variant
Source: rs762457418
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, stop_retained_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109557129C>T
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109559082T>G

(Homo sapiens)
Allele/Variant
Source: NC_000012.12:g.109559082T>G
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109559082T>G
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109559149C>T

(Homo sapiens)
Allele/Variant
Source: rs2136195257
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109559149C>T
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109568865T>C

(Homo sapiens)
Allele/Variant
Source: rs2084305079
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, splice_acceptor_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109568865T>C
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109568877T>C

(Homo sapiens)
Allele/Variant
Source: NC_000012.12:g.109568877T>C
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109568877T>C
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109571636G>C

(Homo sapiens)
Allele/Variant
Source: NC_000012.12:g.109571636G>C
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109571636G>C
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109571640C>T

(Homo sapiens)
Allele/Variant
Source: NC_000012.12:g.109571640C>T
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109571640C>T
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109571659C>A

(Homo sapiens)
Allele/Variant
Source: NC_000012.12:g.109571659C>A
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109571659C>A
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109561795G>T

(Homo sapiens)
Allele/Variant
Source: rs763783083
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109561795G>T
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109561829G>A

(Homo sapiens)
Allele/Variant
Source: rs371092213
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109561829G>A
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109565134G>A

(Homo sapiens)
Allele/Variant
Source: rs769385276
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, stop_gained, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109565134G>A
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109555281T>C

(Homo sapiens)
Allele/Variant
Source: rs886048917
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109555281T>C
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109555343C>T

(Homo sapiens)
Allele/Variant
Source: rs117011771
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109555343C>T
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109553954G>A

(Homo sapiens)
Allele/Variant
Source: rs186602321
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109553954G>A
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB

(GRCh38)12:109556307A>C

(Homo sapiens)
Allele/Variant
Source: rs11831226
Genes: MMAB (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)12:109556307A>C
Gene Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type...cblB