Version: 8.0.0Date: Tue Jan 28 2025
Category
Gene Ontology
Source: GO:0035175
Synonyms:
- histone kinase activity (H3-S10 specific)
- histone serine kinase activity (H3-S10 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:1990244
Synonyms:
- histone H2A-T120 kinase activity
- histone kinase activity (H2A-T120 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0044025
Synonyms:
- histone kinase activity (H2B-S14 specific)
- histone serine kinase activity (H2B-S14 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0004711
Synonyms: Not Available
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0072354
Synonyms:
- histone H3-T3 kinase activity
- histone kinase activity (H3-T3 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0035403
Synonyms:
- histone H3-T6 kinase activity
- histone kinase activity (H3-T6 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0004677
Synonyms: Not Available
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0072371
Synonyms:
- histone H2A-S121 kinase activity
- histone kinase activity (H2A-S121 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Source: GO:0004694
Synonyms: Not Available
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0004679
Synonyms:
- 5'-AMP-activated protein kinase activity
- AMPK activity
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0140857
Synonyms:
- histone kinase activity (H3-T45 specific)
- histone threonine kinase activity (H3-T45 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0035979
Synonyms:
- histone H2AS139 kinase activity
- histone kinase activity (H2A-S139 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0044024
Synonyms:
- histone kinase activity (H2A-S1 specific)
- histone serine kinase activity (H2A-S1 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0140855
Synonyms:
- histone kinase activity (H3-S57 specific)
- histone serine kinase activity (H3-S57 specific)
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Rno)...Lrrk1 (Mmu)...LRRK1 (Hsa)
Gene Ontology
Source: GO:0004672
Synonyms:
- protamine kinase activity
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Mmu)...LRRK1 (Hsa)...Lrrk1 (Rno)
Gene Ontology
Source: GO:0005525
Synonyms: Not Available
Branch: molecular function
Genes: lrrk1 (Dre)...Lrrk1 (Mmu)...LRRK1 (Hsa)...Lrrk1 (Rno)
Gene Ontology
Source: GO:0106310
Synonyms:
- protein-serine kinase activity
Branch: molecular function
Genes: Lrrk1 (Mmu)...LRRK1 (Hsa)
Disease
Source: DOID:14330
Definition: A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Genes: Lrrk1 (Mmu)...LRRK1 (Hsa)...Lrrk1 (Rno)
Gene Ontology
Source: GO:0035556
Synonyms:
- intracellular signal transduction pathway
- intracellular signaling cascade
Branch: biological process
Genes: Lrrk1 (Mmu)...LRRK1 (Hsa)...Lrrk1 (Rno)
Gene Ontology
Source: GO:0004674
Synonyms:
- protein serine kinase activity
- protein serine-threonine kinase activity
Branch: molecular function
Genes: lrrk1 (Dre)...LRRK1 (Hsa)...Lrrk1 (Rno)
sa13187
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130530-349
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
sa13125
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130411-2781
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
sa13011
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130411-2681
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
sa40838
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6976
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
sa30882
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-680
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
sa12644
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130411-2352
Genes: lrrk1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: lrrk1 (Dre)
Gene Ontology
Source: GO:0016310
Synonyms: Not Available
Branch: biological process
Genes: lrrk1 (Dre)
Gene Ontology
Source: GO:0000166
Synonyms: Not Available
Branch: molecular function
Genes: lrrk1 (Dre)...LRRK1 (Hsa)
Lrrk1
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0319307
Genes: Lrrk (Dme)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Parkinson's disease 8
Variant Name: Not Available
Symbol: Lrrk1
Name: Lrrk1
Gene Ontology
Source: GO:0006338
Synonyms:
- ATP-dependent chromatin remodeling
- ATP-dependent chromatin remodelling
Branch: biological process
Genes: Lrrk1 (Mmu)...Lrrk1 (Rno)...LRRK1 (Hsa)
(GRCh38)15:100973826G>A
(Homo sapiens)Allele/Variant
Source: rs2031114890
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100973826G>A
(GRCh38)15:100973837G>A
(Homo sapiens)Allele/Variant
Source: rs2031116479
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100973837G>A
(GRCh38)15:100924704A>C
(Homo sapiens)Allele/Variant
Source: NC_000015.10:g.100924704A>C
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100924704A>C
(GRCh38)15:100973942A>G
(Homo sapiens)Allele/Variant
Source: rs1249255322
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100973942A>G
(GRCh38)15:100973986C>T
(Homo sapiens)Allele/Variant
Source: rs962406905
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100973986C>T
(GRCh38)15:100988698G>T
(Homo sapiens)Allele/Variant
Source: rs199710239
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100988698G>T
(GRCh38)15:100988758G>T
(Homo sapiens)Allele/Variant
Source: rs757519760
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100988758G>T
(GRCh38)15:100989243C>T
(Homo sapiens)Allele/Variant
Source: rs1033685337
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100989243C>T
(GRCh38)15:101010446G>A
(Homo sapiens)Allele/Variant
Source: rs377162968
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101010446G>A
(GRCh38)15:101010474C>G
(Homo sapiens)Allele/Variant
Source: rs368549166
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101010474C>G
(GRCh38)15:101021893C>T
(Homo sapiens)Allele/Variant
Source: rs201182477
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101021893C>T
(GRCh38)15:100988688G>A
(Homo sapiens)Allele/Variant
Source: rs200548454
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100988688G>A
(GRCh38)15:101022495G>A
(Homo sapiens)Allele/Variant
Source: rs2033843622
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101022495G>A
(GRCh38)15:100988807A>G
(Homo sapiens)Allele/Variant
Source: rs35985016
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)15:100988807A>G
(GRCh38)15:101024806G>C
(Homo sapiens)Allele/Variant
Source: rs2033946833
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101024806G>C
(GRCh38)15:101024881G>T
(Homo sapiens)Allele/Variant
Source: rs758131541
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101024881G>T
(GRCh38)15:101024941C>G
(Homo sapiens)Allele/Variant
Source: rs562726580
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101024941C>G
(GRCh38)15:101025952T>C
(Homo sapiens)Allele/Variant
Source: rs369704933
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101025952T>C
(GRCh38)15:101026060C>T
(Homo sapiens)Allele/Variant
Source: rs972179032
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101026060C>T
(GRCh38)15:101027698C>T
(Homo sapiens)Allele/Variant
Source: rs758619910
Genes: LRRK1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)15:101027698C>T