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1,873 results for Ang2

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Ang2

(Mus musculus)

Gene

Name: angiogenin, ribonuclease A family, member 2

Synonyms: angiogenin related protein, Rnase5b, Raa2, Ang, Angrp

Source: MGI:104984

Biotype: protein coding gene

Symbol: Ang2 (Mmu)

Symbol: Ang2

Strict Orthology Symbols: Ang2

Alleles: Ang2 (Mmu)

Ang2

(Rattus norvegicus)

Gene

Name: angiogenin, ribonuclease A family, member 2

Synonyms: LOC108348324, angiogenin-like, Raa2, angiogenin, ribonuclease, RNase A family, 5, ribonuclease A a2, Ang, angiogenin ribonuclease 2

Source: RGD:1359373

Biotype: protein coding gene

Symbol: Ang2 (Rno)

Symbol: Ang2

Strict Orthology Symbols: Ang2

Ang2^em1Gpt

(Mus musculus)

Allele/Variant

Source: MGI:7309784

Genes: Ang2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ang2 (Mmu)

Genes: Ang2 (Mmu)

Symbol: Ang2^em1Gpt

Gene (1)

ANGPT2

(Homo sapiens)

Gene

Name: angiopoietin 2

Synonyms: angiopoietin-2, LMPHM10, ANG2, angiopoietin-2a, angiopoietin-2B, ANG-2, Tie2-ligand, AGPT2

Source: HGNC:485

Biotype: protein coding gene

Synonyms: ANG2...ANG2

Angpt2

(Mus musculus)

Gene

Name: angiopoietin 2

Synonyms: Ang2, Ang-2, Agpt2

Source: MGI:1202890

Biotype: protein coding gene

Synonyms: Ang2...Ang2...Ang2

angpt2b

(Danio rerio)

Gene

Name: angiopoietin 2b

Synonyms: angpt2, ang2

Source: ZFIN:ZDB-GENE-010817-2

Biotype: protein coding gene

Synonyms: ang2...ang2

Synonyms: ribonuclease A A1, HEL168, RNASE5, RNase 5, MGC22466, ribonuclease 5, RNASE4, ALS9, Homo sapiens epididymis luminal protein 168, epididymis luminal protein 168, MGC71966, RAA1, angiogenin, ribonuclease, RNase A family, 5, ribonuclease A family member 5

Source: HGNC:483

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

vps51

(Danio rerio)

Gene

Name: VPS51 subunit of GARP complex

Synonyms: fat-free, ffr, ang2, wu:fi30b05, fi30b05, fat free, c11orf2

Source: ZFIN:ZDB-GENE-030131-6008

Biotype: protein coding gene

Synonyms: ang2...ang2

angpt2

(Xenopus tropicalis)

Gene

Name: angiopoietin 2

Synonyms: angpt2, angiopoietin 2, ang-2, ang2

Source: Xenbase:XB-GENE-487765

Biotype: gene

Synonyms: ang2...ang2

Disease (23)

angpt2.S

(Xenopus laevis)

Gene

Name: angiopoietin 2

Synonyms: angiopoietin 2, ang-2, ang2, angpt2.S

Source: Xenbase:XB-GENE-17333302

Biotype: gene

Synonyms: ang2...ang2

angpt2.L

(Xenopus laevis)

Gene

Name: angiopoietin 2

Synonyms: angpt2.L, angiopoietin 2, ang-2, ang2

Source: Xenbase:XB-GENE-17333301

Biotype: gene

Synonyms: ang2...ang2

Ang4

(Mus musculus)

Gene

Name: angiogenin, ribonuclease A family, member 4

Synonyms: Rnase5d, Raa2, Ang

Source: MGI:2656551

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

rnasel2

(Danio rerio)

Gene

Name: ribonuclease like 2

Synonyms: Dr-RNase2, zf-rnase-2, si:ch211-139g14.6, RNase ZF-2

Source: ZFIN:ZDB-GENE-050208-420

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

Ang6

(Mus musculus)

Gene

Name: angiogenin, ribonuclease A family, member 6

Synonyms: predicted gene, EG630952, EG630952, Raa2, Ang

Source: MGI:3528602

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

Ang

(Mus musculus)

Gene

Name: angiogenin, ribonuclease, RNase A family, 5

Synonyms: AI385586, Rnase5a, angiogenin, ribonuclease A family, member 1, Raa2, Ang1, expressed sequence AI385586

Source: MGI:88022

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

Ang5

(Mus musculus)

Gene

Name: angiogenin, ribonuclease A family, member 5

Synonyms: Raa2, Ang

Source: MGI:3528599

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

Ang3

(Mus musculus)

Gene

Name: angiogenin, ribonuclease A family, member 3

Synonyms: Rnase5c, Raa2, Ang, Angl

Source: MGI:1201793

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

Disease (23)

rnasel3

(Danio rerio)

Gene

Name: ribonuclease like 3

Synonyms: im:6907218, Dr-RNase1, zf-rnase-3, RNase ZF-3

Source: ZFIN:ZDB-GENE-050809-5

Biotype: protein coding gene

Strict Orthology Symbols: Ang2

VPS51

(Homo sapiens)

Gene

Name: VPS51 subunit of GARP complex

Synonyms: ANG2, vacuolar protein sorting 51 homolog, ANG3, FLJ13879, chromosome 11 open reading frame 3, PCH13, FLJ36472, FFR, fat-free homolog, vacuolar protein sorting-associated protein 51 homolog, C11orf3, C11orf2, VPS51, GARP complex subunit, another new gene 2 protein, VPS51 GARP complex subunit

Source: HGNC:1172

Biotype: protein coding gene

Synonyms: ANG2...ANG2

amyotrophic lateral sclerosis type 9

Disease

Source: DOID:0060200

Definition: An amyotrophic lateral sclerosis that has_material_basis_in mutation in the ANG gene on chromosome 14.

Genes: Ang2 (Rno)...Ang2 (Mmu)

Gene (12)

trophoblastic neoplasm

Disease

Source: DOID:4085

Definition: A germ cell and embryonal cancer that derives_from trophoblastic tissue.

Genes: Ang2 (Mmu)...Ang2 (Rno)

Gene (40)

XB5802829

(Xenopus tropicalis)

Gene

Name: amphinase-4-like

Synonyms: FRL2, XB5802829, amphinase-4-like, LOC100496462

Source: Xenbase:XB-GENE-5802830

Biotype: gene

Strict Orthology Symbols: Ang2

Disease (23)

Angpt2^tm1Gdy

(Mus musculus)

Allele/Variant

Source: MGI:3040929

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Angpt2^{tm1c(KOMP)Seq}

(Mus musculus)

Allele/Variant

Source: MGI:5613889

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

la013481Tg

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-120806-8372

Genes: angpt2b (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: ang2

Gene (1)

Angpt2^{tm1(ANGPT2)Smoc}

(Mus musculus)

Allele/Variant

Source: MGI:7626375

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Gene (1)

Angpt2^{tm2(Angpt1)Gdy}

(Mus musculus)

Allele/Variant

Source: MGI:3040930

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Angpt2^tm1.1Yuhe

(Mus musculus)

Allele/Variant

Source: MGI:6280652

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Gene (1)

Angpt2^em1(IMPC)Mbp

(Mus musculus)

Allele/Variant

Source: MGI:6158462

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

activation of phospholipase A2 activity

Gene Ontology

Source: GO:0032431

Synonyms:

phospholipase A2 activation

Branch: biological process

Genes: Ang2 (Mmu)

Genes Annotated with this GO Term (7)

Angpt2^em2Smoc

(Mus musculus)

Allele/Variant

Source: MGI:7750338

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Gene (1)

Angpt2^em1Smoc

(Mus musculus)

Allele/Variant

Source: MGI:7288254

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Gene (1)

Angpt2^em1Gpt

(Mus musculus)

Allele/Variant

Source: MGI:7376206

Genes: Angpt2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: Ang2

Gene (1)

angiogenin-PRI complex

Gene Ontology

Source: GO:0032311

Synonyms:

angiogenin-placental ribonuclease inhibitor complex

Branch: cellular component

Genes: Ang2 (Mmu)

Genes Annotated with this GO Term (13)

cell growth involved in cardiac muscle cell development

Gene Ontology

Source: GO:0061049

Synonyms:

cardiac muscle cell hypertrophy
cardiomyocyte growth

Branch: biological process

Genes: Ang2 (Mmu)...Ang2 (Rno)

Genes Annotated with this GO Term (47)

renal absorption

Gene Ontology

Source: GO:0070293

Synonyms:

nephron absorption
renal reabsorption

Branch: biological process

Genes: Ang2 (Mmu)...Ang2 (Rno)

Genes Annotated with this GO Term (135)

cardiac muscle hypertrophy

Gene Ontology

Source: GO:0003300

Synonyms: Not Available

Branch: biological process

Genes: Ang2 (Mmu)...Ang2 (Rno)

Genes Annotated with this GO Term (147)

ihb826

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-241107-6

Genes: vps51 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: ang2

Gene (1)

angiotensin-activated signaling pathway

Gene Ontology

Source: GO:0038166

Synonyms:

angiotensin II-mediated signaling pathway
angiotensin receptor signaling pathway

Branch: biological process

Genes: Ang2 (Rno)...Ang2 (Mmu)

Genes Annotated with this GO Term (61)

antifungal humoral response

Gene Ontology

Source: GO:0019732

Synonyms: Not Available

Branch: biological process

Genes: Ang2 (Mmu)

Genes Annotated with this GO Term (32)

diacylglycerol biosynthetic process

Gene Ontology

Source: GO:0006651

Synonyms:

diacylglycerol anabolism
diacylglycerol biosynthesis

Branch: biological process

Genes: Ang2 (Mmu)

Genes Annotated with this GO Term (32)

rRNA transcription

Gene Ontology

Source: GO:0009303

Synonyms:

rRNA biosynthesis
rRNA biosynthetic process

Branch: biological process

Genes: Ang2 (Mmu)

Genes Annotated with this GO Term (149)

Effect of CVX-060 treatment on hepatic gene expression of cirrhotic rats

(Rattus norvegicus)

HTP Dataset Index

High-Throughput (HTP) Dataset Index metadata provided by RGD

ID: GEO:GSE122822

Tags: unclassified

Summary: Currently, the therapeutic prospects for cirrhosis patients are limited to liver transplantation and, therefore, there is an urgent need to develop new therapeutic strategies for improved treatments. Cirrhosis was induced in male Wistar rats with CCl4 treatment, and RNA from the complete livers was extracted and quantified through microarray experiments. Angiopoietins signalling is a key pathway in blood vessel normalization. Angiopoietin 1 (Ang1)-Tie2 signalling stabilizes blood vessels, Angiopoietin 2 (Ang2) on the other hand is a context-dependent antagonist of Ang1 and decreases its stabilizing effect giving rise to immature blood vessels. Cirrhotic conditions are characterized by higher expression and activity of Ang2 than healthy conditions, resulting in the loss of blood vessels stability. Previous work showed that inhibition of Ang2 via CVX-060 enhances Ang1-Tie2 signalling, and can stabilize the vascular system in cirrhotic livers. We therefore performed RNA extraction after treatment of cirrhotic rats with CVX-060 during 4 weeks. We observed changes in expression state (expressed/not expressed) in key transcription factors previously implicated in cirrhosis.